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As regulatory expectations continue to evolve in the area of pharmaceutical development, working with contract research and manufacturing organizations that couple execution experience with high-end technical capabilities and contemporary quality systems will ensure the most value from strategic partnerships and enhance a project’s progress on its path toward commercialization.
NIRS is an analytical technique based on absorption measured in the near-infrared region of the electromagnetic spectrum that is between the visible and the mid-infrared regions...
STEMdiff™ APEL™ Medium is an animal component-free formulation that enables reliable differentiation of human ES cells and iPS cells. Developed by STEMCELL Technologies and based on a published formulation1, STEMdiff™ APEL™ Medium supports differentiation into ectoderm, mesoderm and endoderm lineages...
In the laboratory, weighing is only one step of a whole analysis chain in drug discovery and quality control; however it strongly influences the overall quality and integrity of the final result. Proper weighing is thus essential to ensure continuous adherence to predefined process requirements and to avoid a frequent…
The developmental versatility of pluripotent stem cells (PSCs) offers a powerful approach for directing cell fate, and these cells are a promising source of progenitors and terminally differentiated somatic cells for cell replacement therapy and drug screening applications.
Changes in ISO 14644-1 to improve confidence in quality for critical life-science applications. Tony Harrison, UK Subject Matter Expert to ISO TC209 Working Group.
HIV research using human primary cells: despite intense research in the 30 years since the discovery of HIV/AIDS, the disease remains a global epidemic with no credible vaccine available.
This whitepaper offers a detailed analysis of the differences between AccuGENX-ID™ and the MicroSEQ® v2.0* methodologies in obtaining an accurate identification.
Download this free white paper for detailed insight into the advantages of autoantibodies as biomarkers, including a review of the current technology and best practices for identification of sensitive and specific autoantibody biomarkers.
Dr John Rossi is Chair and Professor of the Department of Molecular and Cellular Biology at the Beckman Research Institute of City of Hope (Duarte, CA). His research focuses on the biology and applications of eukaryotic small RNAs and, in particular, their therapeutic use in HIV/AIDS and cancer.
RNA-Seq is a powerful sequencing-based method that enables researchers to discover, profile, and quantify RNA transcripts across the entire transcriptome.
Profiling of putative lead compounds against a representative panel of important enzymes, receptors, ion channels and transporters is an excellent way to establish a preliminary view of potential issues that might later hamper development.
