App Note: PAT success
Read how CAMO Software is working in the PAT (Process Analytical Technology) space to offer customers market leading software solutions for PAT applications...
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Whitepapers & App Notes
Application Note: Evolving promising leads
The precision of data from surface plasmon resonance (SPR)-based analyses, and the confidence with which results can be interpreted, is strongly coupled to the sensitivity of the SPR sensor. Biacore™ T200 system from GE Healthcare offers excellent sensitivity that enables detection of the lowest molecular-weight interactions and accurate measurements at…
App Note: How does the analysis of biomolecules benefit from UHPLC?
Ultra high performance liquid chromatography (UHPLC) provides improved separation speed, throughput, and sensitivity by employing stationary phase particles of around 2μm or smaller.
Application Note: Analysis of Compound Combination Experiments
With recent improvements in automation and liquid handling, compound combination experiments can be executed at higher throughput than ever before. However, software tools have not kept up with this increase and often still require either a manual, percombination workflow or cover just the synergy calculation without the necessary pre-processing steps.…
Application Note: Raman Analysis of Pharmaceutical Ingredients
A range of options is available for Raman analysis, including systems suitable for handheld, laboratory and educational applications. Systems typically include a spectrometer, laser, operating software and sampling accessories, while modular options are available for users to configure their own Raman systems. Setups are available for various wavelength ranges and…
Application Note: Anthocyanin purification from blackcurrant with SCPC-100
The blackcurrant is the edible berry of a shrub, which usually grows to 1-2 meters and can be found in Northern/Central Europe and Asia.
App Note: Controlled supersaturation experiments to check the time that additives keep drugs in solution
Controlled Supersaturation experiments provide a way to create supersaturated solutions which can then be monitored to determine the precipitation rate and the time when precipitation starts. This is illustrated using bifonazole, a basic drug with pKa of 6.0.
Technical Sheet: Charles River Accugenix® MALDI-TOF enhancements for bacterial identifications enable improved root cause analysis
Library coverage is often a topic of discussion for microbiologists wanting to know what the impact or relevancy of the Charles River Accugenix® library databases is on the identification of environmental, EM or industrial microorganisms.
Whitepaper: Chemical characterisation of diverse pharmaceutical samples by Confocal Raman Microscopy
Confocal Raman Microscopy (CRM) is extremely useful for drug substance design, for patent infringement and counterfeit analysis.
Whitepaper: Sampling Guidelines for Handheld Raman Measurements; What You Need To Know
As we see increased adoption of Raman Spectroscopy as the technique of choice for the rapid identification of materials, our guidelines tell you what you need to know...
Validation Study of the Vi-CELL™ XR for Automated Cell Counting of Dendritic Cells
The Vi-CELL XR is an automated cell counting and viability analyzer that uses the trypan blue dye exclusion method...
App Note: Benefits of library and identification method transfer capabilities using hand-held Raman spectrometers
Identification of materials using spectral libraries and other multivariate identification methods on hand-held Raman spectrometers has allowed for rapid non-destructive analysis and easy interpretation of results for non-technical users...
App Note: Following the progress of pharmaceutical mixing studies using near-infrared spectroscopy
This free-to-view Application Note shows the possibility to apply near-infrared spectral information for monitoring the pharmaceutical mixing process...
Whitepaper: Duolink® Technology – Illuminating Insight into Protein Interactions by HCS
Alongside established drug target classes, innovative approaches are addressing previously undruggable target classes such as protein–protein interactions.
Whitepaper: Advantages of Online 2D UPLC for MRM Quantification of Therapeutic Monoclonal Antibodies in Serum
This application note demonstrates the development of a two-dimensional chromatographic assay for the quantification of trastuzumab, providing up to a three-fold increase in sensitivity compared to 1D LC/MRM.
