Application Note: Rocking Motion cultivation
The BIOSTAT® Rocking Motion (RM) bioreactor system ensures optimal process control and cell growth for all single-use cell culture applications.
List view / Grid view
Whitepapers & App Notes
Application Note: MALDI-ToF Mass Spectrometry – A valid alternative for microbial identification
MALDI-ToF mass spectrometry, a phenotypical RMM for microbial identification, is a unique, highly accurate alternative method that facilitates cost-effective, precise and rapid data acquisition.
Application note: Enhancing reaction understanding with online NMR reaction monitoring – application to chemical route development
11 January 2016 | By Anna L. Dunn, Analytical Research and Development, Pfizer, Department of Chemistry, University of Wisconsin / Anna Codina, Bruker UK Limited / David A. Foley and Mark T. Zell, Analytical Research and Development, Pfizer
In this work, we demonstrate the complementarity of NMR and infrared (IR) spectroscopy and show the use of NMR to improve the understanding and robustness of the synthesis of an active pharmaceutical ingredient (API) precursor...
Application Note: Direct measurement of challenging target-ligand interactions
GE Healthcare’s most sensitive SPR-based sensor enables accurate interaction analysis of LMW fragments binding to difficult targets.
Application Note: A phenotypic assay for metastasis
BioTek demonstrate a method for the generation of 3D spheroidal structures using a co-culture of a human breast cancer cell line and human fibroblasts embedded in an invasion matrix containing CXCL12 as chemoattractant...
Whitepaper: Enhanced Raman reflection spectroscopy for process analytical technology
This note describes the use of enhanced Raman reflection spectroscopy to accomplish analysis on multi-layered samples similar to many pharmaceutical tablets...
Poster note: MALDI high-throughput screening beyond 100,000 samples per day in drug discovery
This work focuses on the improvement of MALDI-TOF automation parameters to further increase sample analysis speed in HTS assays to more than 100,000 samples per day...
Application note: Raman monitoring of active coating composition
This application note demonstrates the suitability of Raman spectroscopy using Kaiser’s unique noncontact large-spot PhAT technology to monitor of active coating composition.
eBook: Pharma Serialisation – Where to Begin
By the end of 2018, 75% of the world’s prescription medications will be protected by legislation - this eBook explains the basic fundamentals of pharma serialisation...
Whitepaper: Development and optimization of CHOgro® transient expression technologies for high titer antibody production in suspension CHO cells
During early stage drug development, quickly obtaining relevant candidate proteins through transient transfection can accelerate drug discovery.
Whitepaper: Multiplexed cancer immune response analysis nCounter® PanCancer Immune Profiling Panel for gene expression
The ability of mutated cells to give rise to pathological cancer relies upon the capability of these cells to evade immune recognition, suppress immune activity, and persist in a chronically inflamed environment. Tremendous growth in the understanding of these complex processes is beginning to generate breakthroughs in the treatment of…
Application note: High-throughput Screening of Deubiquitylase enzyme (DUB) activity/specificity and inhibitor screening by MALDI-TOF mass spectrometry
In biopharmaceutical laboratories, there is a growing need for high-throughput, yet sensitive methodologies to characterize deubiquitylase enzymes (DUBs) and DUB inhibitors...
Whitepaper: Current trends in Raman Spectroscopy for Upstream Bioprocess Monitoring and Control
This application note covers some new trends in bioprocess monitoring and control focusing on the increasing use of Kaiser Optical Systems Raman spectrometers as multi-measurement bioprocess sensors to enable quality by design, process optimization, process control and continuous processing...
Case Study: Perceptive Engineering
Perceptive Engineering discusses a two year collaborative R&D project it undertook to address challenges associated with the new generation of reactor systems used in production...
Whitepaper: Analysis of a Mammalian cell culture
In this free whitepaper we discuss real-time, in situ bioprocess understanding in accordance with the PAT initiative and comparison of Raman and NIR spectra of cell culture components...
