Applications note: Raman-based nutrient control in bioprocessing optimizes viable cell density and protein glycation
In this application note, Kaiser Optical Systems, Inc. discuss raman-based nutrient control in bioprocessing...
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Whitepapers & App Notes
Case study: Application of SORS (RapID) to In-Container Testing of Raw Materials
In this case study, Cobalt Light Systems discusses Application of SORS (RapID) to In-Container Testing of Raw Materials...
Whitepaper: Possible Mechanism of Low Endotoxin Recovery
Since the risks of LER relate to the reversible biological activity change of endotoxin, it is worth reviewing previous papers on the aggregation of purified lipopolysaccharide (LPS) and its biological activity. The purpose of this article is to discuss the potency change of endotoxin in the LER by reviewing previous…
Quantification of Tablets Containing Multiple APIs: Using Transmission Raman
The ability to predict multiple constituents of a final dosage form in one fast, non-destructive measurement can reduce analysis time. This is especially important when quantification of multiple APIs is required for tests such as content uniformity, assay and ID...
Whitepaper: Maintaining sample integrity with aerosol-blocking tips
In this whitepaper, find out more about maintaining sample integrity with aerosol-blocking tips...
Whitepaper: Techniques for developing Raw Material Libraries – sampling and scanning
In this whitepaper, find out more about the techniques for developing Raw Material Libraries...
Application note: Raman-based high-throughput screening for version and polymorph identification
In this application note, find out more about the RamanRxn1™ High Throughput Screener (HTS) from Kaiser Optical Systems, Inc...
Application note: Improving quality, efficiency, and chemical process economics using HyperFlux™ PRO Plus real-time reaction monitoring
In this application note, find out how Tornado Spectral System’s HyperFlux PRO Plus Raman spectroscopy system helps overcome limitations...
Application note: Downstream biopharmaceutical operations
This Kaiser application note focuses on real-time, in situ process understanding using a Raman-based PAT approach. Raman spectroscopy is uniquely useful for biotechnology ‘Quality by Design’ (QbD) applications because it enables fast, non-destructive monitoring and control...
Biochemical Assay Development Using Novel MALDI High-Throughput Screening System
This whitepaper focuses on developing biochemical assays where substrate and product are small molecules using a novel MALDI-HTS system...
Application Note: Facilitating filtration of small volumes: HPLC and UHPLC sample prep
Filtrating small volumes of fluid (< 2 mL) can be difficult due to the volume remaining inside the filter after use, so Pall Laboratory have developed 13 mm syringe filters with mini spike outlets for filtration of small volume samples...
Application Note: Method suitability in microbiology: understanding complex cGMP guidelines
Particularly in the pharmaceutical industry, microbiological method development and, specifically, method suitability is often overlooked or left until the end of a project. However, it is important to give both method suitability and development due consideration as it can be a complicated process involving wide specifications, vague parameters and the…
Whitepaper: SWILE pick & decision dispense
Chemspeed's SWILE technology is the first fully automated true one-to-one gravimetric "pick & decision dispense" of compounds...
Whitepaper: Raman Spectroscopy for Polymer Analysis
Find out how recent advances in technology have made Raman spectroscopy better and more affordable for polymer analysis than traditional IR spectroscopy...
Poster note: Fully automated structure verification of organic compounds by combining high resolution accurate MS with NMR data analysis
Here we describe a new approach which automates structure verification for (synthetic) chemists...
