Whitepaper: Influence of different lubricants on tabletting characteristics and dissolution behaviour
Posted: 5 June 2019 | JRS Pharma | No comments yet
Lubricants have a far more wide-reaching impact on the characteristics of the finished tablet than merely easing their means of production. A study was carried out to investigate precisely what those effects were.
Apart from their desired effect of reducing the ejection force and punch adhesion, lubricants also have a considerable influence on the tablet hardness, disintegration, and dissolution times due to their inherent hydrophobicity. This study aimed to investigate the influence of the lubricant molecular structure on the aforementioned characteristics.
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Related topics
Active Pharmaceutical Ingredient (API), Analytical techniques, Drug Manufacturing, Excipients, Formulation, Manufacturing, Processing, Production, Research & Development (R&D)
