Whitepapers/App Notes/Posters

Whitepaper: Sensitive and flexible bacterial endotoxin testing with the EndoZyme® II Recombinant Factor C Assay using the Synergy™ HTX Microplate Reader

Posted: 13 December 2017 | | No comments yet

This article covers how the EndoZyme II assay is established, optimised and validated using the SynergyTM HTX Multi-Mode Microplate Reader with Gen5TM software…

EndoZyme® II is a bacterial endotoxin test for pharmaceuticals and medical devices as well as their in-process intermediates and raw materials. The assay relies on recombinant horseshoe crab Factor C (rFC), an exact synthetic copy of the endotoxin-sensitive enzyme naturally harboured by the blood of horseshoe crabs. Compared with methods sourced from these animals, rFC methods offer better specificity, flexibility, lot-to-lot consistency and, importantly: a sustainable and secure source.

 

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