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Whitepaper

Science of scale for spray-dried intermediates

Speed to market is a critical aspect of developing new pharmaceutical products, and scale-up – or scale-down – can play a key part in that process.

Speed to market is a critical aspect of developing new pharmaceutical products, and scale-up – or scale-down – can play a key part in that process. Significant interest has been focused on the science of scale for spray drying, since this process is the leading technology for formulating drugs with slow dissolution rates or poor solubility, which results in low bioavailability. Compounds with these challenging properties – estimated at 70% of the compounds in drug pipelines today – have a narrow window of absorption in the small intestine, reducing the amount of drug absorbed into the body and significantly decreasing efficiency.

Lonza has over 20 years of experience in the scale-up and scale-down of spray drying processes. To learn more, read our whitepaper.

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