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Viruses

Left-handed gold nanoparticles improve vaccine efficacy by more than 25 percent, finds study

20 April 2022 | By Mandy Parrett (European Pharmaceutical Review)

The results of a recent international study suggest that left-handed gold nanoparticles can increase vaccine effectiveness by 25 percent, providing useful adjuvant capabilities.

news

Recipharm builds biologics presence with acquisitions

12 April 2022 | By Hannah Balfour (European Pharmaceutical Review)

The closing of two biologics acquisitions will help Recipharm establish itself in the advanced therapy medicinal products space.

drug products of various forms in various types of packaging, including liquid in glass vials and pills/capsules in blister packages - idea of medicines or pharmaceuticals

news

EMA human medicines committee (CHMP) meeting highlights, March 2022

28 March 2022 | By Hannah Balfour (European Pharmaceutical Review)

The March meeting saw the EMA’s Committee for Medicinal Products for Human Use (CHMP) recommend five medications for approval including a multiple myeloma gene therapy.

idea of mRNA vaccine development - vaccine and a SARS-CoV-2 virus wrapped by an mRNA strand

news

Moderna launches two new mRNA vaccine programmes

24 March 2022 | By Hannah Balfour (European Pharmaceutical Review)

The new mRNA vaccine programmes are aimed at the major causative agents of respiratory tract infections, respiratory syncytial virus (RSV), influenza and coronaviruses.

news

New preventative medicine for COVID-19 authorised in UK

22 March 2022 | By European Pharmaceutical Review

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has reported that Evusheld, developed by AstraZeneca, has been granted approval to help protect against the effects of COVID-19.

news

Potential for a new one-and-done COVID-19 treatment

18 March 2022 | By Mandy Parrett (European Pharmaceutical Review)

Investigational drug Lambda reduced risk of COVID-19-related death in one of the largest studies of its kind to date.

Close-up of female doctor spraying a nasal spray

news

First participants dosed with pan-antiviral nasal spray in Phase IIa trial

16 March 2022 | By Hannah Balfour (European Pharmaceutical Review)

The Phase IIa influenza-challenge study will enrol 123 healthy adults and support the development of INNA-051 as a pan-antiviral nasal spray.

vaccine development concept - glowing blue syringe, viral particles and vaccine vials all on a darker blue background

news

mRNA vaccine candidates for HIV enter Phase I trial

14 March 2022 | By Hannah Balfour (European Pharmaceutical Review)

Will mRNA vaccines one day protect against HIV? Three investigational mRNA vaccines, all designed to combat HIV, have entered Phase I testing.

news

Could AAT be the answer to COVID-19 ARDS?

14 March 2022 | By Hannah Balfour (European Pharmaceutical Review)

Clinical study finds alpha-1 antitryspin (AAT) reduces pro-inflammatory IL-6 and therefore may benefit COVID-19 patients with Acute Respiratory Distress Syndrome (ARDS).

aedes aegypti mosquito on human skin - the vector for diseases including Zica virus, Dengue, Chikungunya and Mayaro fever

news

Chikungunya vaccine candidate safe and immunogenic in Phase III

8 March 2022 | By Hannah Balfour (European Pharmaceutical Review)

Valneva’s single-shot chikungunya vaccine candidate, VLA1553, offered a very high level of seroprotection in all adults, including the elderly.

article

Prioritising bold innovation throughout the pandemic and beyond

22 February 2022 | By Chinmay Bhatt

Following his first full year as Managing Director UK, Ireland & Nordics for Novartis Pharmaceuticals, healthcare leader Chinmay Bhatt shares his learnings from the pandemic and reflects on what’s next.

article

Challenges in downstream purification of advanced therapies

22 February 2022 | By John Liddell (CPI)

John Liddell, Chief Technologist at the Centre for Process Innovation (CPI), writes about the challenges associated with gene therapy products, which constitute a major portion of the overall cell and gene therapy market.

news

Cabenuva HIV treatment approved for eight week dosing

3 February 2022 | By European Pharmaceutical Review

US FDA approves Cabenuva (cabotegravir, rilpivirine) based on results from the ATLAS-2M Phase IIIb trial which showed every-two-month dosing was non-inferior to once-monthly dosing.

tobacco plants for molecular pharming in a laboratory

news

Plant “biofactories” produce proteins for potential COVID-19 vaccine

3 February 2022 | By Hannah Balfour (European Pharmaceutical Review)

Transiently infecting tobacco plants, researchers were able to produce recombinant proteins that could be developed into COVID-19 vaccines.

news

Could COVID-19 vaccines be swallowed?

2 February 2022 | By Hannah Balfour (European Pharmaceutical Review)

New pre-clinical research demonstrates the potential of gastric autoinjectors to deliver mRNA in sufficient quantities for vaccination.

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Viruses