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Drug combination may become new standard treatment for advanced kidney cancer
Immunotherapy drug plus targeted agent provided better progression-free survival and shrank tumors in more patients than standard one-drug treatment...
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Therapeutics
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Pricing dispute over cystic fibrosis drug Orkambi continues in the UK
Campaigners call for UK Government to intervene on pricing dispute over cystic fibrosis drug Orkambi...
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Developing the production of the radioisotope Tc-99m within the US
A team of university researchers have collaborated together to develop a method to produce the radioisotope Tc-99m in the US to prevent having to import it...
whitepaper
Application Note: Quantitation of intact therapeutic protein in plasma matrix by LC/MS
A complete workflow to quantify intact therapeutic proteins in plasma matrix has been developed, covering three critical components in preclinical sample analysis: target protein enrichment/purification, LC/MS data acquisition and quantitative data analysis.
whitepaper
Whitepaper: Characterising antibody-drug conjugates using micro pillar array columns combined with mass spectrometry (μPAC™-MS)
The use of micro pillar array columns (μPAC™) for characterising antibody-drug conjugates is presented. Kadcyla® (ado-trastuzumab emtansine) and, for comparison, Herceptin® (trastuzumab) tryptic digests were analysed on a 200 cm μPAC™ C18 column and peaks eluting were detected by ultraviolet (UV) spectroscopy and high-resolution mass spectrometry (MS).
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Drug delivery to the brain using scorpion venom
IRB researchers have developed a method to use a peptide found in chlorotoxin identified in scorpion venom to deliver drugs through the blood-brain barrier...
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Immunotherapy success for triple-negative breast cancer
A combination of chemotherapy and immunotherapy could soon be used in NHS hospitals for triple-negative breast cancer to extend patient survival...
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NIAID plan for in-depth tuberculosis research
NIAID has released a plan for research in the infectious disease TB in order to strengthen efforts and resolve to attack this disease...
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Pioneering radiotherapy machine treats its first patient in the UK
Improved accuracy and fewer patient side effects are among the benefits claimed for the pioneering radiotherapy machine...
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Is cancer fundraising fuelling deceit?
Researchers questioned whether cancer crowdfunding elicits deception, especially when offering patients treatments with no scientific backing...
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NHS announces groundbreaking personalised child cancer treatment
The NHS has announced a groundbreaking new treatment, CAR-T, for children with leukaemia...
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Gene therapy receives Champalimaud Vision Award
The Champalimaud Vision Award has been awarded to research teams for the development of a gene therapy...
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FDA approves the first drug with an indication for treatment of smallpox
The US Food and Drug Administration has approved TPOXX (tecovirimat), the first drug with an indication for treatment of smallpox...
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The MERIT of working with microalgae
Algenuity, based in Stewartby, Bedfordshire, is celebrating the successful launch of the MicroalgaE as Renewable Innovative green cell facTories project, MERIT, a three-year ERA CoBioTech project financed under the Horizon 2020 programme...
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FDA approves Epidiolex derived from marijuana, for severe epilepsy
The FDA has approved Epidiolex oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy...
