news
Machine learning may reveal cause-effect relationships in protein dynamics data
A group of researchers is showing how artificial intelligence approaches can help identify cause-effect relationships within data...
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Proteins
news
Programming DNA to deliver cancer drugs
New technology could lead to the development of new cancer therapies...
news
Scientists share promising results of BET and EZH2 inhibitors for lymphoma
Researchers at the TAT (Targeted Anticancer Therapies) International Congress 2018 in Paris have presented new epigenetics compounds that show early activity in lymphoma patients.
news
Online tool provides 3-D view of human metabolic processes
An international team of researchers has developed a computational resource that provides a 3D view of genes, proteins and metabolites involved in human metabolism...
news
IL-18 inhibitor drug holds great potential for inflammatory diseases
An international team of researchers has identified the key role that IL-18 protein plays in Still’s disease, making it a prime candidate for IL-18 inhibitor drug that is proving promising in current trials.
news
Blood and urine tests developed to indicate autism in children
International researchers believe that their new blood and urine tests which search for damage to proteins are the first of their kind to detect early autism spectrum disorders...
news
Robotic method isolates high-producing cell lines for HIV vaccine production
Technical advances in vaccine production should shorten the time to clinical trials, breaking the logjam of promising new candidate vaccines waiting to be tested...
whitepaper
Application Note: Raman-based nutrient control in bioprocessing optimizes viable cell density and protein glycation
Production of protein therapeutics by mammalian cells is the most widely used bioprocess because of its ability to properly produce and fold a recombinant protein...
whitepaper
Whitepaper: pAVEwayTM – microbial expression system for the efficient large scale production of therapeutic proteins
pAVEway™ is an innovative expression system in E. coli that enables rapid creation of novel recombinant strains and the development of downstream processes that ensure industry leading product titres and efficient scale-up of the production of proteins of therapeutic utility...
whitepaper
Whitepaper: Downstream biopharmaceutical operations
The work presented here investigates the development and application of new bioprocess analytics in accordance with the aims of QbD...
news
Blood-based epigenetic may hold clues to autism
Epigenetic data reveals immune-response pathways that may prove critical to understanding autism...
webinar
Application of HDX-MS for drug discovery and development
13 October 2017 | By Thermo Fisher Scientific
In this webinar, theory and practice of HDX-MS will be discussed in conjunction with the topics of pharmaceutical industry...
whitepaper
Whitepaper: Raman-Based Nutrient Control in Bioprocessing Optimises Viable Cell Density and Protein Glycation
Production of protein therapeutics by mammalian cells is the most widely used bioprocess because of its ability to properly produce and fold a recombinant protein...
whitepaper
Poster: Accelerate antibody drug development with subdomain-specific affinity ligands
Scientists from Thermo Fisher Scientific discuss how the CaptureSelect affinity purification products and analytical tools have been developed for the discovery and manufacturing of therapeutic antibodies, including novel formats such as bi-specific antibodies and Fc-fusion proteins...
article
Subvisible particle identification in protein-based formulations by Raman spectroscopy
Subvisible particles in protein-based formulations can have different origins. Particles can be extrinsic (unexpected foreign material), intrinsic (from the production environment or primary packaging), and inherent (from the formulation). It is important that inherent particles (protein agglomerates) are distinguished from the other two types and that the extrinsic and intrinsic…
