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The particle size of Active Pharmaceutical Ingredients (API) has a significant effect on a drug product’s manufacturability and performance. With respect to manufacturability, particle size can affect compatibility, flowability and blend uniformity; with respect to product performance it can affect solubility, dissolution, and bioavailability.
In this issue: investment in biopharmaceuticals, particle size methods, and unlocking the potential of new technologies like Lab-on-a-chip.
FPS has provided High Containment Integrated systems within aseptic condition...
Microtrac unveils a new generation of particle analyzers. Microtrac’s Sync is synchronizing size and shape measurement – one sample, one bench, one sample flow path, one sample cell, one analysis...
Malvern Panalytical, the experts in materials characterization, is pleased to announce the launch of three exciting new systems which will be on display at Pittcon 2018 in Orlando, FL from 27 February through 1 March...
Particle size reduction is a fast and cost-effective answer to increasing the exposure of poorly soluble oral drugs by increasing surface area and thereby improving dissolution rate. This approach will only work for DCS IIa1 drugs where dissolution rate is the rate-limiting factor for absorption. This may be applicable to…
Light-emitting nanoprobes can detect cancer early and track the spread of tiny tumours...
5 September 2016 | By Biopharma Group
Fluid processing requirements are becoming ever more stringent, and so high pressure homogenisation is increasingly surfacing as a solution to meeting these needs...
22 October 2015 | By John Carpenter, University of Colorado / Amber Haynes, Fradkin KBI Biopharma / Christina Vessely, Biologics Consulting Group Inc.
Quantifying and sizing subvisible particles in biopharmaceutical products are crucial aspects of formulation development, stability studies, process development, product release and extended characterisation of the final drug product.
In Issue #4 2014: Protein Expression, Multivariate Data Analysis, Informatics in-depth focus, Particle Sizing, Lean Manufacturing, NIR In-depth focus, X-Ray Fluorescence and much more...
