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Microbeads to combat infection show promise in burn wound simulations
A potential alternative to antibiotics, protein-coated beads block bacteria from binding host cells...
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Microbiology
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Bacteria therapy shows promise for eczema
Topical treatment with live Roseomonas mucosa was found to be safe for adults and children with atopic dermatitis...
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LC-TEM provides a window into the nanoscale
Researchers create a device that allows more electron beam to pass through liquid samples...
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Specificity in the recombinant factor C test for endotoxin
Limulus amebocyte lysate (LAL) users, compendial experts and regulators are still orienting themselves to the recombinant factor C (rFC) assay. Changes to compendial standards do not occur overnight and, for now, users willing to change must perform the alternative validation procedure USP .
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The changing environment in pyrogen and endotoxin testing
Pyrogen testing of drug products for parenteral administration is a mandatory task. Regulatory authorities require that each batch of drug product is pyrogen-free. Historically, the rabbit pyrogen test (RPT) was the required test but in most cases can be replaced by the endotoxin specifi c Limulus Amebocyte Lysate (LAL) test.
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The latest trends in pharmaceutical microbiology
There have been many changes in pharmaceutical microbiology as we progressed into the 21st century. Some of these changes have been due to the advance of rapid microbiological methods, knowledge gained from the study of the human microbiome, while others are changes to conventional testing methods. This paper discusses some…
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FDA authorises new use of test to identify the emerging pathogen Candida auris
The FDA has authorised the first test to identify the emerging pathogen Candida auris, which can cause serious infections in hospitalised patients...
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Could statins ease deadly heart condition in rare neuromuscular disease?
Penn study shows that cholesterol drug may help Friedreich's ataxia patients...
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Microbiology In-Depth Focus 2018
In this In-Depth Focus; specificity in the recombinant factor C test for endotoxin, the latest trends in pharmaceutical microbiology, and the changing environment in pyrogen and endotoxin testing.
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Issue #2 2018 – Digital Version
In this issue; recent developments in turning promising compounds into drug candidates, reviewing the latest trends in pharmaceutical microbiology and their implications, and a roundtable debate featuring the views of five industry leaders.
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Developing a 3D bioink for use in regenerative medicine
The concept of developing a bioink that can be used for all cell types and all printing techniques is at best unrealistic and at worst impossible. What is much more achievable and also more desirable is a modifiable, modular system...
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Scientists design new skin cell culture technique to study HPV
Novel approach enables genetic analysis of entire viral life cycle, starting with initial infection...
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Wickham Labs to exhibit at inaugural Making Pharmaceuticals Europe Conference 2018
Wickham Laboratories Ltd will exhibit on Stand 408 at the Making Pharmaceuticals Europe Conference, from the 13 - 14 March 2018 in Belgium at Brussels Expo centre...
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Old antibiotic compounds could become tomorrow’s life-saving drugs
Scientists and chemists are re-examining old compounds to see whether they could hold the key to a future drug to combat increasingly resistant bacteria...
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Robotic method isolates high-producing cell lines for HIV vaccine production
Technical advances in vaccine production should shorten the time to clinical trials, breaking the logjam of promising new candidate vaccines waiting to be tested...
