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Lab-on-a-chip

 

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Microfluidics in cell-to-cell signalling measurements

30 June 2016 | By ,

Hormones are secreted molecules that carry biological information between cells. This type of cell-to-cell communication is vital to human life, and its dysregulation often underlies disease. In fact, the largest known class of cell surface receptors involved in hormone communication, G-protein coupled receptors, are also the largest class of known…

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Microfluidic chips: Lab-on-a-chip cell culture for metabolomics

3 July 2015 | By Laura A. Filla and James L. Edwards, Saint Louis University

Microfluidic devices (MFDs) have recently become popular as cell culture platforms for metabolomics due to reduced reagent requirements and the feasibility of flow-based studies. Such devices have the potential to transform pharmaceutical research by providing an online approach to high-throughput screening which can be coupled with a variety of analysis…