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Microcapsules to enhance the efficiency of genome-editing
Researchers have found that polymer and hybrid silica-coated microcapsules are efficient in genome-editing...
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Formulation
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Smart bandage could promote better, faster healing
Researchers have collaborated to design a smart bandage that could eventually heal chronic wounds...
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Engineering approach combines drugs to control parasitic worms
Researchers have developed a technology - that can quickly identify potential drug combinations to control parasitic worms...
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Parkinson’s disease drug carbidopa shows anticancer effects
Research shows the Parkinson's disease drug carbidopa displays significant anticancer effects in human cell lines...
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TLR agonists suppress tumour growth
TLR agonists injected directly into a tumour suppresses tumour growth throughout the whole body...
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Metal simplifies synthesis of antibody drugs
Scientists have developed a method to efficiently modify natural antibodies that can deliver drugs to target cells...
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Quality control of freeze-dried oral formulations; challenges when developing novel approaches for the delivery of poorly-soluble drugs
A common obstacle encountered in the early stages of drug development is the formulation of poorly water-soluble drugs (PWSDs). One effective approach to improve the dissolution of PWSDs is to render such drugs into their amorphous or disordered form. However, amorphous materials are both physically and chemically unstable, and tend…
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Injectable tissue patch may help repair damaged organs
Researchers have developed a technique that lets them use a small needle to inject a repair patch, without the need to open the chest cavity...
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New injectable antiretroviral treatment for HIV patients
A phase II clinical trial has paved the way to the implantation of all-injectable antiretroviral therapies with a lower frequency of administration...
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Double network hydrogels make drug-releasing systems safer
Double network hydrogel composed of two interwoven polymer nets to improve the safety of drug-delivery systems that reside within the stomach...
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Freeze-dried formulations: a new perspective on reformulating naloxone
Opioid overdose in the US and in Europe is on the rise, and the role of prescription-sourced drugs such as oxycodone cannot be underestimated...
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Raman Spectroscopy In-Depth Focus
In this Raman Spectroscopy In-Depth Focus: Subvisible particle identification in protein-based formulations by Raman spectroscopy; Raman spectroscopy as a blood glucose monitoring tool...
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Subvisible particle identification in protein-based formulations by Raman spectroscopy
Subvisible particles in protein-based formulations can have different origins. Particles can be extrinsic (unexpected foreign material), intrinsic (from the production environment or primary packaging), and inherent (from the formulation). It is important that inherent particles (protein agglomerates) are distinguished from the other two types and that the extrinsic and intrinsic…
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Formulation Development & Delivery In-Depth Focus
In this Formulation Development & Delivery In-Depth Focus: A report on the use of freeze-drying to develop orally disintegrating tablets; a review of mucosal drug delivery; an interview on drug delivery through the skin; and a profile of three analytical technologies used to develop drug delivery systems...
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Scientific Poster Gallery 2017
In this supplement, we've brought together a collection of interesting posters from leading companies in order to celebrate cutting-edge research in the pharmaceutical industry and to share with our readers some of the varied work being carried out by their colleagues...
