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FDA accepts NDA for ALKS 5461 for major depressive disorder
The FDA has accepted for review the New Drug Application for ALKS 5461, a novel, once-daily, oral investigational medicine for the adjunctive treatment of major depressive disorder ...
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Nivolumab reduces size of some lung cancer tumours, relapse rate after surgery
A drug given to early-stage lung cancer patients before they undergo surgery showed major tumour responses in the removed tumour...
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Iron supplements may influence the development of colon cancer
Two common iron compounds increase the formation of a known biomarker for cancer...
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HRT trial demonstrates improved memory function in adrenal patients
Better timing for cortisol replacement therapies, to more closely replicate the secretion patterns of people with normal levels of the hormone, has shown a significant improvement in patients' cognitive function...
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Study examines antipsychotic medication for children with autism
Children with intellectual difficulty or autism are more likely to be given antipsychotic medication from a younger age than those without intellectual disability...
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Metformin may help with nicotine withdrawal
A drug that has helped millions of people around the world manage their diabetes may also help people ready to kick their nicotine habits...
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Benzodiazepines can help depression
New research points to the important role that benzodiazepines may have in depression...
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Larotrectinib shows promise in paediatric patients with TRK gene mutations
A new cancer drug has proven safe and effective for paediatric patients with a rare tumour gene mutation...
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Flare-responsive hydrogel developed to treat arthritis
Researchers develop a better delivery system for anti-inflammatory therapies...
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Combination immunotherapy improves survival in mouse models of mesothelioma
Combined treatment with two cancer immunotherapy drugs significantly prolonged survival in aggressive cancer malignant mesothelioma...
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EC approves Alofisel for complex perianal fistulae in Crohn’s disease
The EC has approved Alofisel for the treatment of complex perianal fistulae in adult patients with nonactive/mildly active luminal Crohn’s disease...
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Oestrogen levels do not rise for transgender men treated with testosterone therapy
Testosterone therapy is not associated with a rise in oestrogen levels among transgender men, according to a new study led by Boston Medical Center...
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Nicotinamide riboside shows promise for reversing cardiovascular ageing
Nicotinamide riboside was shown to mimic caloric restriction, boosting arterial health...
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Sorafenib improves progression-free survival for patients with rare sarcomas
A randomised clinical trial shows that the drug sorafenib tosylate extended progression-free survival compared with a placebo...
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Opioid analgesics reduce the use of antipsychotics in Alzheimer’s disease
Initiating an opioid analgesic reduced the use of antipsychotics and benzodiazepines in persons with Alzheimer's disease...
