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Flu’s response to Xofluza explored
Scientists are now investigating the Xofluza mode of action in detail and have uncovered possible mechanisms by which viral resistance to it could emerge...
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Drug Targets
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BCG vaccine leads to long-term blood sugar improvement in type 1 diabetes
A study has found a novel mechanism underlying stable, durable blood sugar control...
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Researchers find combination can enhance ipilimumab immunotherapy
Anti-CTLA-4 treatment triggers immune-suppressing EZH2 on T cells; clinical trial open...
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SMC approves Xermelo for carcinoid syndrome diarrhoea
Scotland is the first country in the UK to enable patients, battling this serious and debilitating condition, access to a new treatment option...
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Better outcomes for patients using single-pill combination for hypertension
Findings may represent simple and potentially low-cost intervention...
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Talazoparib shows promise for early-stage BRCA+ breast cancer patients
Once-daily oral pill could replace preoperative chemotherapy in patient population if validated in larger trials...
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Immunosuppressant drugs may protect against Parkinson’s
People who take immunosuppressants are less likely to develop Parkinson's disease...
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Ibrutinib may benefit glioblastoma patients
An FDA-approved drug for lymphoma and leukaemia may also help treat the most common - and deadliest type of brain tumour...
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FDA accepts Larotrectinib New Drug Application and Grants Priority Review
The FDA has accepted the NDA and granted Priority Review for larotrectinib for advanced or metastatic solid tumours harbouring a NTRK gene fusion...
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AIBP injection alleviates chemotherapy pain for months in mice
Protein inhibits inflammatory response underlying chronic pain processing may provide an alternative to opioids for severe, persistent pain...
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Drug-delivering nanoparticles could help fight brain cancer
Nanoparticles carrying two drugs can cross the blood-brain barrier and shrink glioblastoma tumours...
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FDA approves Palynziq for PKU, a rare and serious genetic disease
Novel enzyme therapy for adults with PKU who have uncontrolled blood phenylalanine concentrations with current treatment...
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Experimental drug eases effects of gluten for coeliac patients on gluten-free diet
First proof-of-concept study shows AMG 714 (anti-IL-15 monoclonal antibody) potentially protects celiac patients from inadvertent gluten exposure
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Antidepressant use may be linked to increased risk of weight gain
Prolonged use of antidepressants may lead to increased risk of weight gain...
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FDA approves Prolia for glucocorticoid-induced osteoporosis
The FDA has approved the use of Prolia for the treatment of glucocorticoid-induced osteoporosis (GIOP) in men and women at high risk of fracture...
