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Drug Development

Targeted therapies for chronic lymphocytic leukaemia in an evolving treatment landscape

15 August 2024 | By Dr Mehrdad Mobasher (BeiGene)

Dr Mehrdad Mobasher, Chief Medical Officer for Hematology, BeiGene, discusses the evolution of therapies for chronic lymphocytic leukaemia (CLL), the promise of targeted treatments and what could be on the horizon of the therapeutic landscape for this disease.

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Innovative vaccine demonstrates sustained malaria immunisation in pregnancy

15 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

Follow up research to the presented findings could provide improved opportunities for preventing malaria in women during pregnancy.

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First-in-class therapy approved for chronic skin disease

14 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The biologic treatment targets a key driver of prurigo nodularis, with trial data demonstrating improved itch as well as skin nodules for patients with the condition.

news

Sustainable QC method for antimicrobial quantification

13 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The new, cost-effective fluorimetric approach could help to mitigate clinical demand for the treatment of multidrug-resistant (MDR) bacterial infections.

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MSD set to acquire novel antibody for B-cell malignancies

12 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The next-generation B-cell depletion biologic therapy has demonstrated promise in B-cell malignancies and autoimmune diseases.

news

HDFN drug trial shows capability for alloimmune diseases

9 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

Based on the new data, nipocalimab could change the standard of care for treating the rare blood disease haemolytic disease of the foetus and newborn (HDFN).

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Regulating therapies for rare diseases – recent approvals

8 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

This article summarises some of the recent notable drug approvals in the EU and US, including a gene therapy and an enzyme replacement therapy.

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Personalised mRNA cancer therapy shown to boost immune response

8 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The individualised neoantigen therapy could enable a precise, durable immune response, based on study findings in melanoma and lung cancers.

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Genentech-Sangamo deal to advance neurodegenerative treatments

7 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

Overall, Sangamo Therapeutics will be eligible up to $1.9 billion from Genentech, which includes various milestone and royalty payments.

news

Downstream process shows potential for oncolytic virus purification

6 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The paper presents an “efficient and scalable GMP-compliant process” for purifying a fusogenic oncolytic virus (rVSV-NDV).

whitepaper

Science of scale for spray-dried intermediates

5 August 2024 | By

Speed to market is a critical aspect of developing new pharmaceutical products, and scale-up – or scale-down – can play a key part in that process.

news

FDA approves innovative engineered cell therapy

2 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The accelerated approval by the US Food and Drug Administration (FDA) authorises the first engineered cell therapy for a solid tumour in the US.

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Alzheimer’s drug development roundup – July 2024

1 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

From exciting data on cell therapy and monoclonal antibodies, through to new regulatory developments, this article summarises some of the key developments within the Alzheimer’s therapeutic landscape over July.

news

Achieving VLP continuous production with digital twins

1 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

Utilising a digital twin for an advanced process control strategy facilitates additional productivity gains of 20 percent at 99.9 percent reliability, the authors shared.

news

From biologics to small molecules – the shift in biopharma’s revenue growth

31 July 2024 | By Catherine Eckford (European Pharmaceutical Review)

Biopharma companies that experienced strong revenue growth due to COVID-19 drug sales have been overtaken by companies that developed obesity drugs in 2023, GlobalData suggests.

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Drug Development