news
High doses of favipiravir may be effective against Ebola
High doses of favipiravir extended survival in non-human primates infected with Ebola virus, according to a new study....
List view / Grid view
Dosage
news
Study of childhood asthma cautions against short-term high-dose treatment with steroids
Researchers in the US have found that a common practice among physicians to increase the use of steroids for worsening symptoms of asthma in children may be associated with slowing a child’s rate of growth.
article
Packaging In-Depth Focus 2018
This Packaging In-Depth Focus explores the risks around interactions between drugs and their packaging and looks at how smart packaging may help patients take their medication accurately.
news
Short-acting asthma relievers linked to infertility
New research indicates that women with asthma who only use short-acting asthma relievers take longer to become pregnant than other women...
article
Non-clinical dose formulation considerations
Designing appropriate non-clinical safety studies requires thoughtful, and sometimes experimental, consideration of the delivery methodology for the therapeutic. The choice of formulation affects drug release and absorption and has a direct impact on the pharmacokinetic profile and associated response of the model system. The formulation should be compatible with the…
news
Shorter treatment course better for intermediate risk prostate cancer?
New research suggests that treatment with a shorter course of radiation using higher doses over fewer days may be the preferred approach for some men with intermediate-risk prostate cancer.
news
FDA approves new dosing for Xarelto to reduce the risk of VTE
The FDA has approved the 10 mg once-daily dose of Xarelto, for reducing the continued risk of recurrent venous thromboembolism...
news
Dual antithrombotic therapy cuts bleeding risk
Researchers have found that using just two anti-clotting medicines for atrial fibrillation is safer than using the current standard treatments...
news
EU approval for Regeneron and Sanofi’s rheumatoid arthritis drug
The European Commission (EC) has granted marketing authorisation for Regeneron and Sanofi’s Kevzara (sarilumab) for the treatment of rheumatoid arthritis...
news
PDA issues essential new guidance for visual inspections
A new technical report has clarified best practice on visual inspection for visible particles in parenterals.
news
Rise in product recalls prompts FDA to warn of possible BCC contamination
The US Food and Drug Administration (FDA) has advised manufacturers of non-sterile, water-based drug products that there have been recent product recalls due to Burkholderia cepacia complex (BCC) contamination.
article
Improving the consistency of MDI drug delivery
A defining characteristic of inhaled drug delivery is variability in the dose received by the patient, as a result of physiology, for example, or the technique applied during use. This variability directly affects clinical outcomes so reducing it to a minimum is an important goal for the industry...
news
Put it to the test
10 January 2017 | By Charles Ischi AG | Kraemer Elektronik
EPM talks to Charles Ischi about the best approach to selecting testing equipment for oral solid dosage applications...
news
Experts analyse growth in the finished dosage market ahead of CPhI Worldwide launch
6 June 2016 | By CPhI
The new Finished Dosage Formulation (FDF) event will be the first global pharma platform dedicated to the manufacture, development and supply of finished dosage forms...
article
Hot melt extrusion processing for the development of sustained release products
15 April 2014 | By Dennis Douroumis, Reader in Pharmaceutical Sciences at the University of Greenwich and the Director of Centre for Innovation in Process Engineering and Research
Hot Melt Extrusion (HME) has attracted increased interest for the development of pharmaceutical dosage forms over the last decade. It is a versatile processing technology which produces extrudates in the form of solid dispersions and solid solutions. Among the various applications, HME has been adopted for the development of sustained…
