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Larotrectinib shows promise in paediatric patients with TRK gene mutations
A new cancer drug has proven safe and effective for paediatric patients with a rare tumour gene mutation...
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Taking a standard prostate cancer drug with food boosts impact
By taking Zytiga with a low-fat meal could decrease the daily dose and prevent digestive issues...
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High doses of favipiravir may be effective against Ebola
High doses of favipiravir extended survival in non-human primates infected with Ebola virus, according to a new study....
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Study of childhood asthma cautions against short-term high-dose treatment with steroids
Researchers in the US have found that a common practice among physicians to increase the use of steroids for worsening symptoms of asthma in children may be associated with slowing a child’s rate of growth.
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Packaging In-Depth Focus 2018
This Packaging In-Depth Focus explores the risks around interactions between drugs and their packaging and looks at how smart packaging may help patients take their medication accurately.
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Short-acting asthma relievers linked to infertility
New research indicates that women with asthma who only use short-acting asthma relievers take longer to become pregnant than other women...
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Non-clinical dose formulation considerations
Designing appropriate non-clinical safety studies requires thoughtful, and sometimes experimental, consideration of the delivery methodology for the therapeutic. The choice of formulation affects drug release and absorption and has a direct impact on the pharmacokinetic profile and associated response of the model system. The formulation should be compatible with the…
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Shorter treatment course better for intermediate risk prostate cancer?
New research suggests that treatment with a shorter course of radiation using higher doses over fewer days may be the preferred approach for some men with intermediate-risk prostate cancer.
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FDA approves new dosing for Xarelto to reduce the risk of VTE
The FDA has approved the 10 mg once-daily dose of Xarelto, for reducing the continued risk of recurrent venous thromboembolism...
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Dual antithrombotic therapy cuts bleeding risk
Researchers have found that using just two anti-clotting medicines for atrial fibrillation is safer than using the current standard treatments...
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EU approval for Regeneron and Sanofi’s rheumatoid arthritis drug
The European Commission (EC) has granted marketing authorisation for Regeneron and Sanofi’s Kevzara (sarilumab) for the treatment of rheumatoid arthritis...
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PDA issues essential new guidance for visual inspections
A new technical report has clarified best practice on visual inspection for visible particles in parenterals.
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Rise in product recalls prompts FDA to warn of possible BCC contamination
The US Food and Drug Administration (FDA) has advised manufacturers of non-sterile, water-based drug products that there have been recent product recalls due to Burkholderia cepacia complex (BCC) contamination.
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Improving the consistency of MDI drug delivery
A defining characteristic of inhaled drug delivery is variability in the dose received by the patient, as a result of physiology, for example, or the technique applied during use. This variability directly affects clinical outcomes so reducing it to a minimum is an important goal for the industry...
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Put it to the test
10 January 2017 | By Charles Ischi AG | Kraemer Elektronik
EPM talks to Charles Ischi about the best approach to selecting testing equipment for oral solid dosage applications...
