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Oil and hydrogel mix effective for precise dosing of medicine
Researchers have developed a new mixture of oil and hydrogel that releases drugs in a controlled fashion, preventing overdosing.
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Comparative evaluation of pharmaceutical powder flow using different analytical methodologies
Glidants and lubricants are important additives in the production of solid dosage formulations. This article compares the results of various methods to characterise the flowability of blends, demonstrating the importance of considering the impacts that glidants may have, not only on the flowability of blends, but the physical attributes of…
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EMA announces restrictions to cyproterone use due to meningioma risk
After a review of cyproterone, the EMA has recommended that the drug only be prescribed once other treatment options have failed, due to an increased meningioma risk.
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Researchers find one dose of HPV vaccine as effective as other regimens
A study investigating the effectiveness of HPV vaccines has revealed that a single dose is as successful at preventing cervical cancer as multiple doses.
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Spotlight: a dispersible tablet formulation to treat HIV in children
A novel formulation for dolutegravir has been developed to improve HIV treatment options for children. Dr Kimberly Smith from ViiV Healthcare discusses the benefits of this new dispersible tablet.
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FDA announces US recall of mirtazapine tablets due to mislabelled strength
Aurobindo Pharma USA, Inc. has issued a voluntary nationwide recall of certain mirtazapine tablets as bottles labelled as 7.5mg may contain 15mg tablets.
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Intravenous delivery of TB vaccine found to dramatically improve potency in models
New research has shown that intravenous injection of the BCG vaccine dramatically reduces monkey susceptibility to TB bacteria and lung inflammation.
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Zotiraciclib granted Orphan Drug Designation by FDA and EMA
The FDA and EMA have granted Orphan Drug Designation to zotiraciclib, currently the subject of two separate Phase Ib clinical trials in glioblastoma.
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Daratumumab approved for multiple myeloma treatment
The drug daratumumab has been approved for treatment of multiple myeloma, demonstrating increased efficacy when used in combination with other drugs.
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Capsosomes: the revolutionary enzyme carriers
Nature can offer inspiration for the synthesis of more effective drug delivery platforms. In this article, Marc Baiget Francesch discusses the potential of capsosomes as a novel, biocompatible, drug delivery system.
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Artificial DNA can control release of active ingredients from drugs
A team at the Technical University of Munich have made it possible for nano particles to be released in sequence with the use of artificial DNA.
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Higher rifampin doses for TB appear more effective with no greater risks
Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, were shown to kill more TB bacteria in sputum cultures without increasing the adverse effects of treatment, according to a recent randomised controlled trial.
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HRT trial demonstrates improved memory function in adrenal patients
Better timing for cortisol replacement therapies, to more closely replicate the secretion patterns of people with normal levels of the hormone, has shown a significant improvement in patients' cognitive function...
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Oral sirolimus alters the course of DIPNECH syndrome
Sirolimus, which is used to prevent rejection after kidney transplants has been used to treat idiopathic pulmonary neuroendocrine cell hyperplasia...
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Larotrectinib shows promise in paediatric patients with TRK gene mutations
A new cancer drug has proven safe and effective for paediatric patients with a rare tumour gene mutation...
