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Whitepaper: Rapid identification of illicit drug substances using thermal desorption coupled with a portable toroidal trap GC/MS system
Whitepaper: Rapid identification of illicit drug substances using thermal desorption coupled with a portable toroidal trap GC/MS system
whitepaper

Application note: Rapid identification of illicit drug substances using thermal desorption coupled with a portable toroidal trap GC/MS system

1 July 2017 | By

This study describes the injection, separation, and identification of 16 drugs compounds in less than 10 minutes using portable gas chromatograph-toroidal ion trap mass spectrometry (PerkinElmer, Torion® T-9 Portable GC/MS) combined with a coiled-wire-filament (CWF) sampling injector to provide an effective tool for onsite analysis of illicit drugs substances...

Scientific Poster Gallery 2017
Scientific Poster Gallery 2017
article

Scientific Poster Gallery 2017

29 June 2017 | By

In this supplement, we've brought together a collection of interesting posters from leading companies in order to celebrate cutting-edge research in the pharmaceutical industry and to share with our readers some of the varied work being carried out by their colleagues...

Universal detection in high performance liquid chromatography
Universal detection in high performance liquid chromatography
article

Universal detection in high performance liquid chromatography

3 July 2015 | By David P. Elder, Phil Borman and George Okafo - GlaxoSmithKline

The most commonly used analytical technique for the testing of drug molecules is reversed-phase high performance liquid chromatography (RP-HPLC) with ultraviolet (UV)/visible detection. However, one of the biggest constraints affecting UV/visible detectors is their inability to generate adequate sensitivity for analytes lacking a suitable UV chromophore.

HPLC: On-chip liquid chromatographic separation
HPLC: On-chip liquid chromatographic separation
article

HPLC: On-chip liquid chromatographic separation

17 April 2015 | By

High-performance liquid chromatography (HPLC) is a powerful separation technique due to its high accuracy, precision, versatility and robustness. In the development of pharmaceuticals, it is no doubt that LC is a key technology in the quality control of pharmaceuticals and pharmacokinetic studies and in the analysis of complex biological compounds…

David Elder
David Elder
article

Can HPLC assay methods really be considered quality critical tests?

5 September 2014 | By

Analytical method specificity is assessed using ICH (International Conference on Harmonisation) Q2 (2005). Although, certain methods are not specific enough for their intended purposes, they may have other advantages. Both titrimetric and UV (Ultra-violet spectroscopy) assays are non-specific, but have superior precision (ca. 0.1-0.5% RSD (Residual Standard Deviation)) compared with…