Whitepaper: Dwell Volume and Extra-Column Volume: What are they and how do they impact method transfer
Method transfer or method scaling across different instrument platforms can be affected by both dwell volume and extra-column dispersion...
List view / Grid view
Method transfer or method scaling across different instrument platforms can be affected by both dwell volume and extra-column dispersion...
Lab Innovations – the UK’s only dedicated showcase for laboratory, analytical and biotech equipment – returns to the NEC, Birmingham, for its sixth consecutive year on the 1st and 2nd of November 2017...
Revolutionary monolithic column technology is now available for large molecule separations; Chromolith® WidePore 300 has different functionalizations to meet chromatographic needs for pharma research.
Dr. Isabelle Francois discusses the advantages of the ACQUITY UPC2 System and its ability to create selective separations of structurally similar chiral and achiral compounds.
Jonathan Turner introduces the CORTECS T3 Column, ideally suited for separating polar and nonpolar compounds in reversed phase chromatography.
Dr. Paula Hong discusses flexibility, sensitivity, and ease of use with the ACQUITY QDa Mass Detector.
Karima Baudin introduces the PerkinElmer QSight™ LC/MS/MS: The Triple Quadrupole Mass Spectrometer that knows the value of time. Discover an exceptional solution for a wide range of applications...
Scientists from Thermo Fisher Scientific discuss how the CaptureSelect affinity purification products and analytical tools have been developed for the discovery and manufacturing of therapeutic antibodies, including novel formats such as bi-specific antibodies and Fc-fusion proteins...
In this Separations & Purifications In-Depth Focus: Experts from Leo Pharma explain how they use an MHC 2D-LC system in their analytical troubleshooting laboratory and how it can be applied to solve key tasks in the lab. Plus, Dave Elder explains how guidance for mutagenic impurities has necessitated control of…
This study describes the injection, separation, and identification of 16 drugs compounds in less than 10 minutes using portable gas chromatograph-toroidal ion trap mass spectrometry (PerkinElmer, Torion® T-9 Portable GC/MS) combined with a coiled-wire-filament (CWF) sampling injector to provide an effective tool for onsite analysis of illicit drugs substances...
Bio-Rad discuss the technique of optimising the purity of a monoclonal antibody using mixed-mode chromatography media...
Classically, isolation of key intermediates and the resultant active pharmaceutical ingredient (API) has formed the basis of clean up and purification strategies within the pharmaceutical industry...
In this supplement, we've brought together a collection of interesting posters from leading companies in order to celebrate cutting-edge research in the pharmaceutical industry and to share with our readers some of the varied work being carried out by their colleagues...
The development and production of antibody biopharmaceuticals and biosimilars require specific chromatographic tools for efficient purification and QC analysis to improve process economics, safety, and time-to-market.
Single-use systems have become an important tool in the development and scale up of biotechnology processes. Single-use systems save space, increase flexibility in scale and space planning and, to a large extent, eliminate cleaning costs in development and change over.