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In this work we report the metabolic analysis of cell cultures using a high-resolution accurate mass LCMS/MS Q-TOF platform to identify metabolite markers of genomics and phenotypic changes.
Many bacterial species have been found to exist in a viable but non-culturable state. Jeanne Moldenhauer discusses this phenomenon and makes suggestions as to why we don’t often see an increase in viable cells when using viability-based methods.
With a continual focus on data integrity and helping our customers meet regulations while generating actionable insights, Particle Measuring Systems provides a complete range of products and services.
Analytical techniques for QA/QC purposes are integral to the safe production of therapeutics. This in-depth focus looks at Raman spectroscopy for amorphous phase analysis and discusses the viable but non-culturable (VBNC) state of bacteria in environmental monitoring.
This application note compares Sartorius' Microsart AMP Mycoplasma kit with two other mycoplasma detection kits that are also based on DNA isolation with subsequent real-time PCR analysis.
The Multitron is the number-one choice for reliable, convenient cultivation of microorganisms and cell cultures. The incubation shaker guarantees homogeneous conditions and delivers reproducible results, leaving nothing to be desired regarding its features and capacity.
This article covers the analytical criteria that apply to Bacterial Endotoxin Testing (BET) using Limulus Amebocyte Lysate (LAL) or recombinant Horseshoe crab Factor C (rFC) for the bioactivity determination of endotoxin in aqueous solutions, such as pharmaceuticals and medical device extracts. It explains the importance of these criteria for accurate…
This poster discusses a process for a 12-week clone development process. The process starts in silico, and progresses through screening and clone selection in 96-deepwell plates up to five liter shaker flasks...
Shimadzu Scientific Instruments (SSI) announces the release of the Cell Culture Media Analysis Platform, C2MAPTM-2000, a fully automated and integrated sample preparation workstation for the analysis of cell culture media...
A technique which allows the continuous production and collection of a cell has been developed removing the limit on the number of cells that can be grown in a culture dish...
ProCellics™, first in-line and real-time bioprocess raman analyser, is a RESOLUTION Spectra Systems product. It offers a GMP user-friendly and easily deployed Process Analytical Technology (PAT) solution...
3 November 2016 | By BBI Solutions
BBI Solutions will be showcasing its Morffi™ signal enhancement technology on Stand F26 in Hall 1 at MEDICA 2016...
The BIOSTAT® Rocking Motion (RM) bioreactor system ensures optimal process control and cell growth for all single-use cell culture applications.
18 December 2012 | By Dr. Stephen Brown, Sheffield RNAi Screening Facility, Biomedical Sciences, University of Sheffield
As RNA interference (RNAi) enters its teenage years from the first critical observations, it has now reached a multi-billion pound industry. There are few research areas that have expanded as quickly and spectacularly as the field of RNAi. The potential of RNAi initially sparked a functional genomics gold rush. Different…
