news
Heroin vaccine could tackle opioid addiction
New research shows that experimental vaccine produces antibodies against commonly misused opioids, including heroin, hydrocodone, oxycodone, hydromorphone, oxymorphone and codeine.
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Antibodies
news
New Lyme disease tests could offer quicker, more accurate detection
New tests to detect early Lyme disease - which is increasing beyond the summer months - could replace existing tests that often do not clearly identify the infection before health problems occur.
webinar
Application of HDX-MS for drug discovery and development
13 October 2017 | By Thermo Fisher Scientific
In this webinar, theory and practice of HDX-MS will be discussed in conjunction with the topics of pharmaceutical industry...
news
Join Dolomite Bio at ASHG 2017
Dolomite Bio is set to display its innovative range of products for high throughput single cell research at the 67th Annual Meeting of the American Society of Human Genetics (ASHG), taking place at the Orange County Convention Center in Orlando, Florida, from the 17th to the 21st of October 2017...
news
EC grants marketing authorisation of Dupixent for atopic dermatitis
Sanofi and Regeneron Pharmaceuticals, Inc. have announced that the EC has granted marketing authorisation for Dupixent for use in adults with moderate-to-severe atopic dermatitis...
whitepaper
Poster: Accelerate antibody drug development with subdomain-specific affinity ligands
Scientists from Thermo Fisher Scientific discuss how the CaptureSelect affinity purification products and analytical tools have been developed for the discovery and manufacturing of therapeutic antibodies, including novel formats such as bi-specific antibodies and Fc-fusion proteins...
whitepaper
Poster: Optimised purity and recovery of a monoclonal antibody using mixed-mode chromatography media
Bio-Rad discuss the technique of optimising the purity of a monoclonal antibody using mixed-mode chromatography media...
article
Personalised medicine, batch size of ONE, the new challenge to fill-finish?
Wenzel Novak PhD gives some considerations on container, environment, process and automation for small batch sizes in the downstream process of fill-finish…
article
Scientific Poster Gallery 2017
In this supplement, we've brought together a collection of interesting posters from leading companies in order to celebrate cutting-edge research in the pharmaceutical industry and to share with our readers some of the varied work being carried out by their colleagues...
whitepaper
Whitepaper: Antibody capture and analysis
The development and production of antibody biopharmaceuticals and biosimilars require specific chromatographic tools for efficient purification and QC analysis to improve process economics, safety, and time-to-market.
whitepaper
Whitepaper: How to choose an antibody?
This whitepaper is a guide offering suggestions to research and clinical laboratories on how to choose an antibody...
article
Mass spectrometry in the development of protein biologics
Biological products, usually referred to as biologics, constitute a significant segment of pharmaceuticals in development. Biologics include therapeutic proteins, antibody drugs, antibody-drug conjugates (ADCs), vaccines, carbohydrates drugs, blood and tissue-derived pharmaceuticals, gene therapies, even live cells and tissues...
article
Approaches in subcutaneous delivery of monoclonal antibodies
Currently, subcutaneous delivery of therapeutic proteins is a fast-growing field, especially for such established modalities as monoclonal antibodies, which require large quantities of drug to be administrated. Different approaches, including high protein concentration, speciality formulations and drug delivery matrices, as well as devices enabling a more rapid administration of larger…
article
Characterising therapeutic antibodies and ADCs using mass spectrometry
Since the 1970s, the advent of biotechnology has resulted in the development and commercialisation of many therapeutic proteins, including antibodies and antibody fragments, for the treatment of human diseases. Examples include antibody treatments for autoimmune diseases (for example, adalimumab [Humira®] for rheumatoid arthritis), cancers (such as trastuzumab [Herceptin®] for breast…
news
Novartis and Xencor enter bispecific antibody collaboration
28 June 2016 | By Victoria White, Digital Content Producer
The collaboration includes XmAb Bispecific Technology for 4 Novartis targets and access to Xencor Fc Technologies...
