news
Trial results show compound makes radiotherapy more effective
A trial has shown that radiotherapy is more effective when levels of ropidoxuridine in a patients' body reach a certain level...
List view / Grid view
Active Pharmaceutical Ingredient (API)
article
LC-MS based multi-attribute method for characterisation and QC testing of protein therapeutics
For several decades mass spectrometry (MS) has been used in the characterisation of protein pharmaceuticals.1-3 However, its use in the laboratory for quality control (QC) product release testing has been quite limited for a number of reasons, for example: instrument complexity and software are not readily amenable to validation, extensive…
article
Biopharma In-Depth Focus 2018
In this issue: investment in biopharmaceuticals, particle size methods, and unlocking the potential of new technologies like Lab-on-a-chip.
news
Pharmacovigilance of new drugs ‘should be more proactive’ in New Zealand
The pharmacovigilance of new drugs and drug formulations undertaken in New Zealand should be proactive, says a leading expert.
news
EU and Japan extend partnership on inspections of medicine manufacturers
The EU and Japan have agreed to widen the range of medicines for which they will recognise each other’s inspections of manufacturing sites.
news
FDA approves Epidiolex derived from marijuana, for severe epilepsy
The FDA has approved Epidiolex oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy...
news
Triboluminescence instrument rapidly tests drug crystallinity
Researchers have created a device that can quickly and inexpensively determine whether new pharmaceutical formulations have trace crystallinity...
news
Iron supplements may influence the development of colon cancer
Two common iron compounds increase the formation of a known biomarker for cancer...
news
Combination immunotherapy improves survival in mouse models of mesothelioma
Combined treatment with two cancer immunotherapy drugs significantly prolonged survival in aggressive cancer malignant mesothelioma...
news
Crystallographic method accelerates drug development
Researchers have developed a novel method that speeds up the process of determining crystal structures of organic salts and significantly reduces the effort required to do so...
news
Programming DNA to deliver cancer drugs
New technology could lead to the development of new cancer therapies...
article
Freeze-dried formulations: a new perspective on reformulating naloxone
Opioid overdose in the US and in Europe is on the rise, and the role of prescription-sourced drugs such as oxycodone cannot be underestimated...
article
Separation and purification applications for mutagenic impurities
Classically, isolation of key intermediates and the resultant active pharmaceutical ingredient (API) has formed the basis of clean up and purification strategies within the pharmaceutical industry...
article
Understanding the effect of API changes in pharmaceutical processing
For the pharmaceutical scientist, the journey of an active molecule from the end of its synthetic pathway and crystallisation to its ultimate site of action is a fascinating one, and one that is necessary to understand...
