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References

Carnell-Morris P, Kaszuba M, Pothecary M. Analytical techniques for faster development of drug delivery systems. European Pharmaceutical Review. 2017; 44-46

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References Global Markets and Technologies for Advanced Drug Delivery Systems BCC Research Reports PHM006K. March 2016. www.bccresearch.com/market-research/pharmaceuticals/advanced-drug-delivery-systems-tech-markets-report-phm006k.html [Accessed 08 November 2016]. Drug Delivery Systems: Getting Drugs to Their Targets in a Controlled Manner. National Institute of Biomedical Imaging and Bioengineering www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner [Accessed 8 November 2016].

Laffleur F. Mucosal delivery – is this the next level in drug delivery?. European Pharmaceutical Review. 2017;3:38-40

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References Laffleur F. Thiomers, mucoadhesion and oral delivery of biomacromolecules. Curr. Drug ther. [Internet]. 2014;9:56-62. Kharenko EA, Larionova NI, Demina NB. Mucoadhesive drug delivery systems (Review). Pharm. Chem. J. 2009. p200-8. Boddupalli B, Mohammed Z, Nath R, Banji D. Mucoadhesive drug delivery system: An overview. J. Adv. Pharm. Technol. Res.…

Courtney P et al. Freeze-dried formulations: a new perspective on reformulating naloxone. European Pharmaceutical Review. 2017;3:32-36

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References National Institute on Drug Abuse: Overdose Death Rates, https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/national-overdose-deaths2015.pdf (Accessed 24 February 2017) www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2015/estimated-deaths-for-the-four-major-cancers-by-sex-and-age-group-2015.pdf Strang J, Bird SM, Parmar MKB. Take-Home Emergency Naloxone to Prevent Heroin Overdose Deaths after Prison Release: Rationale and Practicalities for the N-ALIVE Randomized Trial. Journal of Urban Health-Bulletin of the New York Academy of…

Bhardwaj V, Gaur V. Raman spectroscopy as a blood glucose monitoring tool. European Pharmaceutical Review. 2017;3:26-29

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References International Diabetes Federation. About diabetes, facts and figures 2015 to 2040. Available at: www.idf.org/about-diabetes/what-is-diabetes. Angaran DM, Smith DS, Birnbaum M. The use of urine test for indirect estimation of blood glucose levels in the critically ill. American Journal of Hospital Pharmacy.1980;37:950-956. Clarke SF, Foster JR. A history of blood…

Lankers M, Valet O, Laskina O. Subvisible particle identification in protein-based formulations by Raman spectroscopy. European Pharmaceutical Review. 2017;3:22-24

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References Strehl, R, Rombach-Riegraf V, Diez M, Egodage K, Blueme, M, Jeschke M, Koulov A. Discrimination between silicone oil droplets and protein aggregates in biopharmaceuticals: a novel multiparametric image filter for sub-visible particles in microflow imaging analysis. Pharmaceutical Research. 2012;29(2):594-602. Siska C, Pierini C, Lau H, Latypov R, Fesinmeyer R,…

Gerstberger I, Liebmann M. Regulation of orphan drugs within the EU. European Pharmaceutical Review. 2017;3:14-16

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References Cf. Straeter/Burgardt/Bickmann, Arzneimittel für seltene Leiden – Situation in der Europäischen Union, A&R 2014, 195 with further references. Recital 2 of Regulation (EC) No 141/2000. See also Hiltl, Orphan Drugs – Zwischenbilanz und Konfliktfelder, PharmR 2001, 308. Regulation (EC) No 141/2000 of the European Parliament and of the Council…

Elder D. Separation and purification applications for mutagenic impurities. European Pharmaceutical Review. 2017;3:64-67

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References Fujiwara M, Nagy ZK, Chew JW, Braatz RD. First-principles and direct design approaches for the control of pharmaceutical crystallization. J. Proc. Control. 2005;15:493-504. ICH M7, 2014. Assessment and control of DNA reactive (mutagenic) impurities in pharmaceuticals to limit potential carcinogenic risk. Current Step 4 version. 23 June 2014. Teasdale…

Jacobsen NW, Nielsen LD. Two-dimensional liquid chromatography (2D-LC) with multiple heart-cutting in a troubleshooting laboratory. European Pharmaceutical Review. 2017;3:60-63

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  References Stoll DR, Li X, Wang X, Carr PW, Porter SEG, Rutan SC. Fast, comprehensive two-dimensional liquid chromatography, J Chromatogr A. 2007;1168(1–2):3-43. doi:10.1016/j.chroma.2007.08.054. Pursch M, Buckenmaier S. Loop-based multiple heart-cutting two-dimensional liquid chromatography for target analysis in complex matrices. Anal Chem. 2015;87(10):5310-7. doi: 10.1021/acs.analchem.5b00492. Chen M, Wang L, Dong…