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Particle size reduction is a fast and cost-effective answer to…
3 January 2018 | By Dave Elder, Gene Pacowski, Peter Nelson, Stephen Tindal
Particle size reduction is a fast and cost-effective answer to increasing the exposure of poorly soluble oral drugs by increasing surface area and thereby improving dissolution rate. This approach will only work for DCS IIa1 drugs where dissolution rate is the rate-limiting factor for absorption. This may be applicable to…
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