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UK research consortium given £2 million to control monkeypox
£2 million will help fund a UK team of scientific experts to research monkeypox, uncover novel treatments and curb the spread of the virus.
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University of Edinburgh
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Further £8.4 million in funding given to UK researchers studying immune response to COVID-19
The funding is being split across three research projects that will hopefully improve the treatment of COVID-19 and inform the development of vaccines and therapeutics.
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Clinical trial shows cell therapy could be safe for liver disease patients
A new cell therapy has been tested in patients with liver cirrhosis and found no significant adverse effects.
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Oral anticoagulants and antiplatelets linked to poor outcome in atrial fibrillation
The results challenged the use of combined oral anticoagulant and antiplatelet therapy in patients with atrial fibrillation, especially those without an indication for antiplatelet therapy.
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Aspirin may block bowel tumour formation
Researchers have shed light on how taking aspirin can help to prevent bowel cancer. They found that the painkiller blocks a key process linked to tumour formation...
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Artificial Intelligence improves stroke and dementia diagnosis in CT brain scan
Machine learning has detected one of the commonest causes of dementia and stroke, in the most widely used form of brain scan (CT), more accurately than current methods.
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Painkillers in pregnancy may affect baby’s future fertility
Taking painkillers during pregnancy could affect the fertility of the unborn child in later life, research suggests...
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Cancer drugs could transform the lives of children with AVM
Drugs normally used to treat cancer could reduce the disfigurements of thousands of children born with life-threatening blood vessel defects...
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£54 million funding to transform health through data science
Health Data Research UK is awarding £30 million funding to six sites across the UK to address challenging healthcare issues through the use of data science...
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Stem Cells In-Depth Focus 2015
In this free-to-view Stem Cells In-Depth Focus, you can find out how computational ('in silico') methods can help to rationally choose bioactive small molecules to improve stem cell differentiation. The differentiation of pluripotent stem cells to hepatocyte-like cells is the focus of a second interesting article...
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Label-free quantitative proteomics: Why has it taken so long to become a mainstream approach?
13 June 2013 | By Thierry Le Bihan, SynthSys and Institute of Structural and Molecular Biology, University of Edinburgh
In recent years, mass spectrometry (MS) based proteomics has moved from being a qualitative tool (used to mainly identify proteins) to a more reliable analysis tool, allowing relative quantitation as well as absolute quantitation of a large number of proteins. However, the developed quantitative methods are either specific for certain…
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microRNA manipulation as a host-targeted antiviral therapeutic strategy
13 December 2011 | By Nouf N. Laqtom, University of Edinburgh & King Abdulaziz University and Amy H. Buck, University of Edinburgh
microRNAs (miRNA) are a class of non-coding RNA that regulate the precise amounts of proteins expressed in a cell at a given time. These molecules were discovered in worms in 1993 and only known to exist in humans in the last decade. Despite the youth of the miRNA field, miRNA…
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Applying statistical inference in genomics with evidence based pathways: Towards elucidating new functional correlations of biomarkers
22 February 2010 | By Peter Ghazal, Professor of Molecular Genetics and Biomedicine, University of Edinburgh and Head of Division of Pathway Medicine and Associate Director of Centre for Systems Biology, Edinburgh, Al Ivens, Head of Data Analysis, Fios Genomics Ltd and Thorsten Forster, Statistical Bioinformatician, Division of Pathway Medicine, University of Edinburgh
In conventional pharmacogenomic studies, genetic polymorphisms (including single nucleotide and copy number variations) are elucidated from case-control distribution of individuals usually representing ethnicity, severity of disease, and positive or negative response to treatment. However, the interpretation of a single genetic marker in this context is complicated, as the same marker…
