Swedish Medical Products Agency

article

Using alkali-metal cation recognition of α-cyclodextrin to detect lithium ions by MALDI-TOF

22 February 2023 | By Ahmad Amini, Johan Carlsson

Here, Ahmad Amini and Johan Carlsson from the Swedish Medical Products Agency discuss the use of matrix‑assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) for identification of lithium in pharmaceutical preparations.

article

Identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS

26 February 2019 | By Ahmad Amini, Henrik Lodén, Torgny Rundlöf

Matrix-assisted laser desorption/ionisation (MALDI) time-of-flight (TOF) mass spectrometry (MS) has proven to be an excellent technique for identification of illegally distributed peptides and proteins for human use. The identification of proteins is mainly based on peptide mass fingerprinting (PMF) – ie, the bottom-up approach – while the small proteins and…