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National Health Service (NHS)

UK enhances ILAP to accelerate access to innovative medicines

31 January 2025 | By European Pharmaceutical Review

The MHRA’s refreshed guidance is the only end-to-end access pathway that enables medicine developers to collaborate with the national health system, Regulator, and HTA bodies.

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Innovative pharma-government partnership to enhance UK clinical trials

29 August 2024 | By Catherine Eckford (European Pharmaceutical Review)

The first-of-a-kind investment supports the UK government’s objectives to boost clinical trials, improve patient access to novel treatments and increase competitiveness in life sciences.

article

Understanding the evidence used in drug product withdrawals

14 December 2023 | By Samantha Lane (Drug Safety Research Unit [DSRU])

Samantha Lane, Head of Research for the Centre of Pharmacovigilance Sciences at the Drug Safety Research Unit discusses drug product withdrawals and the regulatory shift to a greater reliance on epidemiological and observational research as evidence for these decisions within Europe.

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First CAR T-cell therapy recommended on NHS

26 January 2023 | By Catherine Eckford (European Pharmaceutical Review)

NICE’s recommendation of Yescarta® means it is the first time patients will be able to access CAR T-cell therapy long-term on the NHS.

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Could ketamine-assisted therapy help treat alcoholism?

19 December 2022 | By Catherine Eckford (European Pharmaceutical Review)

The largest clinical trial of its kind will investigate if ketamine-assisted therapy can reduce harmful drinking in people with severe alcohol use disorder.

news

First adaptive clinical trial for flu

29 November 2022 | By Catherine Eckford (European Pharmaceutical Review)

A £2.9 million trial, the first adaptive platform trial studying flu treatments, could reduce serious illness in patients.

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UK £62 billion behind in R&D global investment share, report reveals

2 November 2022 | By Catherine Eckford (European Pharmaceutical Review)

The IPPR urges the UK government to increase R&D funding to strengthen economic growth and restore the UK’s leading global position.

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MHRA approves Pluvicto^® and Locametz^® for prostate cancer

17 August 2022 | By Hannah Balfour (European Pharmaceutical Review)

The UK’s regulator approved Novartis’ radioligand therapy Pluvicto®▼ and radioactive diagnostic agent Locametz® for use in advanced prostate cancer.

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NICE does not recommend elosulfase alfa for Morquio A syndrome

16 November 2021 | By Anna Begley (European Pharmaceutical Review)

The new draft guidance does not recommend Vimizin (elosulfase alfa) for the treatment of Morquio A syndrome following new evidence.

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NICE recommends first sickle cell disease treatment in 20 years

5 October 2021 | By Anna Begley (European Pharmaceutical Review)

Crizanlizumab recommended as a treatment option for preventing recurrent sickle cell crises for people aged 16 and over in the UK.

Woman holding sore hand, indicating juvenile arthritis

news

NICE recommends tofacitinib for juvenile idiopathic arthritis

10 September 2021 | By Anna Begley (European Pharmaceutical Review)

NICE has recommended Pfizer’s Xeljanz® (tofacitinib) as an option to treat polyarticular juvenile arthritis and juvenile psoriatic arthritis.

Man with plaque psoriasis scratching hands

news

NICE recommends bimekizumab for severe plaque psoriasis treatment

8 September 2021 | By Anna Begley (European Pharmaceutical Review)

Bimzelx® (bimekizumab) becomes the first medicine to be evaluated and recommended through NICE’s new Expedited Low-Risk Fast Track Appraisal.

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NICE approves inclisiran for LDL cholesterol reduction

1 September 2021 | By Anna Begley (European Pharmaceutical Review)

The UK approval follows a Phase III study in which Leqvio® (inclisiran) reduced low-density lipoprotein cholesterol (LDL-C) by 55 percent.

3d rendering pf red blood cells in vein - idea of blood/blood disorder

news

UK patients with rare blood disorders receive new treatment option

20 May 2021 | By Hannah Balfour (European Pharmaceutical Review)

NICE has recommended that Ultomiris (ravulizumab) be available on the NHS for patients with paroxysmal nocturnal haemoglobinuria and atypical haemolytic uraemic syndrome.

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New oral chronic lymphocytic leukaemia treatment made available on NHS

19 March 2021 | By Hannah Balfour (European Pharmaceutical Review)

AstraZeneca’s Calquence (acalabrutinib), a chemotherapy-free monotherapy, will be offered to patients with chronic lymphocytic leukaemia.

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