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EC approves Ipsen’s cabometyx to treat advanced RCC following VEGF-targeted therapy

16 September 2016 | By Niamh Louise Marriott,

The European Commission has approved Ibsen’s cabometyx (cabozantinib) 20, 40, 60 mg tablets for the treatment of advanced renal cell carcinoma (RCC) in adults following prior vascular endothelial growth factor (VEGF)-targeted therapy. Cabometyx (cabozantinib) demonstrated significant clinical benefits across all three efficacy endpoints (OS, PFS, ORR) in a phase 3…

Ergomed and Ferrer complete recruitment for Phase IIa insomnia clinical trial

13 September 2016 | By Niamh Louise Marriott, Digital Content Producer

The effects of lorediplon (5 and 10 mg) are being compared to both placebo and zolpidem. The aim of the study is to evaluate the appropriate effective dose of lorediplon, to further characterise its efficacy on sleep maintenance/sleep quality and to evaluate any next day hangover effects in adult patients…

Major global study reveals new hypertension and blood pressure genes

13 September 2016 | By Niamh Louise Marriott, Digital Content Producer

The discoveries include DNA changes in three rare genes that have much larger effects on blood pressure in the population than previously seen, providing new insights into the physiology of hypertension and suggesting new targets for treatment...

Vasopharm enrols first patient in phase III traumatic brain injury trial

8 September 2016 | By Niamh Louise Marriott, Digital Content Producer

Vasopharm's ronopternin (VAS203) will be evaluated for its safety and efficacy as the first patient is enrolled into the nostra phase III (NO Synthase in TRAumatic Brain Injury) trial – a clinical study to assess whether the drug can be used as a initial treatment for moderately to severely injured…