New Malvern presentation tackles the “overlooked second virial coefficient”
Posted: 11 August 2010 | | No comments yet
Dr Jean-Luc Brousseau has recorded a downloadable presentation that helps illustrate the importance of specific analytical details when characterizing protein or polymer solutions…
Dr Jean-Luc Brousseau has recorded a downloadable presentation that helps illustrate the importance of specific analytical details when characterizing protein or polymer solutions...
Dr Jean-Luc Brousseau from the separations systems team at Malvern Instruments has recorded a downloadable presentation that helps illustrate the importance of specific analytical details when characterizing protein or polymer solutions. In “On the overlooked second virial coefficient” he explains the reasons why and how protein and polymer scientists can improve characterization results by measuring the 2nd virial coefficient, using either static light scattering or gel permeation chromatography/size exclusion chromatography (GPC/SEC). Improved results can then be used to optimize solubility and stability in a final product. This insightful and easy to follow presentation is freely available for download at: http://www.malvern.com/secondvirialcoefficient
Dependent on pH, temperature and other parameters, A2 can be measured using static light scattering in batch or flow using GPC/SEC. Systems from Malvern Instruments’ Zetasizer light scattering range and Viscotek GPC/SEC range, are therefore well suited to measuring A2 in either protein or polymer samples. The new presentation is the latest addition to a comprehensive applications library that can be found at: www.malvern.com
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