Boehringer Ingelheim implements flexible fully disposable up- and downstream manufacturing

Boehringer Ingelheim has developed and now implemented a flexible set-up and operational approach for disposable technologies within its global biopharmaceutical development and manufacturing network.

Regardless of which single use system has been used by customers, Boehringer Ingelheim’s disposable set-up enables that different commercially available single use systems can be operated in the same facility and by the same experts. Boehringer Ingelheim BioXcellence’s™ customers now benefit from an unprecedented level of flexibility while maintaining reliable and efficient project transfers. Besides the novel 100L and 500L GMP (good manufacturing practice) facilities for clinical material supplies the same set-up is in operation for non-GMP process development.

”We have gathered years of experiences from different single use systems in our expert groups and could therefore form a truly unique single use platform for upstream- and downstream processes”, commented Hitto Kaufmann, Vice President Process Science Germany at Boehringer Ingelheim Biopharmaceuticals.

“This platform will be established globally in Boehringer Ingelheim’s mammalian facilities and will support clients globally with the same technology as well as quality standards. It will significantly ease seamless process transfers, smooth outsourcing concepts and further boosts our new and highly flexible Lean-to-Clinic program from gene to drug product in 16 months “.