Pharma Japan 2012: BASF presents its comprehensive and intelligent pharmaceutical solutions

BASF showcases its comprehensive solution profile with solid expertise at Pharma Japan 2012. As a strategic partner to the pharmaceutical industry for more than 75 years, BASF provides intelligent system solutions and high-value products that help its customers to be more successful. BASF exhibits products and services including active pharmaceutical ingredients (APIs), excipients, custom synthesis, building blocks, solvents, reagents, protective groups, and inorganic specialties.

Innovative excipients for better bioavailability enhancement

BASF presents its award-winning solubilizing agent Soluplus® – The Solid Solution. Soluplus® enhances the solubility of drugs and so increases their bioavailability. The product is ideal for innovative pharmaceutical process technologies such as Hot Melt Extrusion (HME) and Spray Drying. BASF has made great strides in regards to solubilization and bioavailability enhancement during recent years, developing innovative solutions for even the toughest solubilization challenges. The company recently published a “Solubilization Compendium”, which is the result of many years of research and provides expert advice on solubilizing compounds with poor solubility and bioavailability profiles. BASF’s Solubilization Compendium is available for download at http://www.innovate-excipients.basf.com.

Kollicoat® IR filed for precedent using in Japan

BASF’s film coating polymer Kollicoat® IR has been filed as a precedent case of use in Japan since April 2012. Kollicoat® IR coating systems for ready-to-use film coatings provide distinctive coloring, robustness and rapid solubility. The toolbox of efficient and environmentally friendly colored film coatings is based on BASF’s 3rd generation Kollicoat® IR polymer. It enables formulators to easily create individual tablet colors on site in countless shades – from only three base colors which has been filed as a precedent case of use in Japan.

Highly concentrated omega-3 fatty acids

With the recent acquisition of Equateq Ltd., a global leader in the manufacturing of highly concentrated omega-3 fatty acids, BASF extends its portfolio of omega-3 products for the pharmaceutical and dietary supplement industries. The company’s proprietary chromatographic separation methods allow flexible formulation of omega-3 fatty acids with variable ratios of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) at concentration levels of up to 99 percent.

Largest metabolite profiling platform

Metanomics Health GmbH, a BASF Group company, combines state-of-the-art metabolite profiling with innovative bioinformatics and data mining systems to enable the discovery and validation of biomarkers. The company provides the globally largest metabolite profiling platform with more than 75 mass spectrometers, and extensive expertise in biomedical interpretation of metabolite fingerprints and pathways, which make the drug discovery and development process more efficient and successful.

First Class APIs from the world leader

For more than 75 years, BASF has been the world-leading supplier of generic active ingredients to the pharmaceutical industry. BASF has long experience as reliable supplier of APIs to the Japanese pharmaceutical market. Customers are valuing BASF’s consistent high-quality standards and regulatory support from locally based experts. BASF’s broad range of APIs includes caffeine, ibuprofen, pseudoephedrine, theophylline, and phenylephrine. In 2013, BASF will extend its portfolio by introducing a pharmaceutical grade of L-menthol to the market.

High-purity iron salts for API manufacturing

BASF has developed an innovative portfolio of high-purity iron salts for API manufacturing based on many years of experience with iron technology. Solutions for iron deficiency anemia and phosphate management during hemodialysis in patients with chronic kidney disease are gaining importance. Therefore, BASF offers a product line with a trace metal content below 1 ppm in compliance with the current regulatory directives. BASF’s high-purity iron salts are available in quantities ranging from kilograms to commercial scale.

Chiral molecules – Intermediates & ChiPros®

BASF offers a broad portfolio of intermediates for the pharmaceutical industry including building blocks, solvents and protective group reagents. This includes achiral as well as chiral products and specialty intermediates. In addition, ChiPros® is a range of chiral amines and amino alcohols for pharmaceutical applications.

Custom synthesis services – Expertise in meeting unique outsourcing needs

BASF is a leading manufacturer of made-to-measure small molecules for the pharmaceutical industry. Offering high-quality and cost-effective services, BASF supports customers throughout the entire life-cycle. Partnering with BASF gives customers access to a global R&D network where value-added technologies are constantly emerging – offering innovative solutions for simplifying production processes and cutting costs.

More information is available at www.pharma.basf.com