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Issue #2 2016 – Digital edition
In this issue: Regulation, Oncology, Single Use, Robotics, Microbiology, PAT, Mass Spectrometry, Drug Delivery, Nanotechnology, and much more...
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Issue 2 2016
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Mass Spectrometry: In-Depth Focus 2016
In this Mass Spectrometry In-Depth Focus: Novel trends in glycosylation analysis of biotherapeutics by mass spectrometry; The use of mass spectrometry for the characterisation of proteins in small molecule drug discovery; Mass Spectrometry Q&A...
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Single Use: In-Depth Focus 2016
In this Single Use In-Depth Focus: Disposables for continuous viral clearance for the production of monoclonal antibodies; Managing the quality of biologics manufactured by single use systems: A Japanese perspective; Single Use Q&A...
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CEIV Pharma: Industry cooperation that is taking off
4 May 2016 | By Ricardo Aitken and Michal Wielgus, IATA Consulting
Several air transport industry stakeholders and regulators have joined forces to create the Center of Excellence for Independent Validators in Pharmaceutical Logistics (CEIV Pharma) programme. This joint effort aims to effectively help reverse the current lack of standardisation, compliance and transparency currently afflicting the pharmaceutical air transport supply chain, via…
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Inhibition of mutant P53 tumour cells by medicinal plants
4 May 2016 | By Osuntokun Oludare Temitope and Ogunleye Adewale Joseph, Adekunle Ajasin University
The aetiology of tumours is attributed to changes in many internal (molecular) factors, most of which include mutations in several regulatory mechanisms and the loss of cell differentiation. Human isoforms of the p53 protein play a key role in maintaining genetic stability, functioning as active tumour suppressors. However, a mutation…
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New trends in intelligent robotics in the laboratory
4 May 2016 | By Dr. Patrick Courtney, tec-connection
While robotics systems have been useful tools in the laboratory for many years, most notably in the area of liquid handling, many tasks are still only automated to a small extent. At the same time a new wave of robotic devices is reaching the market – from robot lawn mowers…
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A novel approach in assessing the antimicrobial efficacy of eye drop products
4 May 2016 | By Mostafa Eissa, Hikma Pharmaceuticals
The microbial contamination of medicinal products constitutes a continuous threat to the health of consumers, which may negatively impact pharmaceutical companies’ reputability. However, multidose sterile pharmaceutical products are prone to contamination either from the normal flora of the human body or from the surrounding environment, following their misuse by patients.…
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Exploring the advantages of PAT for pharmaceutical cleaning in Ireland
4 May 2016 | By Adeyinka Aina, University of Nottingham / Manuel Kuhs, Bernal Powder Engineering Research Group / Shaza Darwish, University of Limerick / Chris Edlin, Pharmaceutical Technology Manufacturing Centre
Process analytical technology (PAT) and its applications have been used in various industrial processes for a long time. It originates from the last century where its first application was in Germany after World War II within the chemical and petrochemical industry1. Following this, it was implemented and refined in different…
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Stem cell nano drug delivery applications to treat diabetes
Stem cell therapy is currently utilised in medicine for its application in tissue repair and regenerative medicine. Unique characteristics of stem cells, such as self-renewal and differentiation, allow its function to be applicable for therapeutic purposes. Nanotechnology and cell microencapsulation have been researched and used as a means to protect…
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Nanotechnology tackles problems with noninvasive glucose monitoring
For diabetes mellitus patients who treat themselves with insulin, the need to self-monitor blood glucose in order to establish their insulin dose is a major burden, and highlights the need to develop non-invasive glucose measurement technologies. Up until now, such non-invasive systems that also have adequate measurement performance under daily…
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An interview with Dr. Timothy S. Oostdyk, Eurofins
Dr. Timothy S. Oostdyk, Group Senior Vice President of Eurofins BioPharma Product Testing, discusses the issues affecting outsourcing to the biopharmaceutical industry and the benefits of having a wide global reach...
