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Sirolimus

FDA awards 11 grants for rare disease treatment developments

15 October 2021 | By Anna Begley (European Pharmaceutical Review)

The FDA has awarded 11 grants equating to about $25 million of funding to clinical trials for the development of rare disease treatments.

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Combining pacritinib with sirolimus-based GvHD prophylaxis may improve efficacy

24 March 2021 | By Hannah Balfour (European Pharmaceutical Review)

Phase I results suggest adding pacritinib to sirolimus and low-dose tacrolimus could be beneficial in preventing graft-versus-host disease (GvHD).

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Oral sirolimus alters the course of DIPNECH syndrome

10 April 2018 | By Dr Zara Kassam (European Pharmaceutical Review)

Sirolimus, which is used to prevent rejection after kidney transplants has been used to treat idiopathic pulmonary neuroendocrine cell hyperplasia...

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Rapamycin treatment prevents crippling heterotopic ossification

12 October 2017 | By Dr Zara Kassam (European Pharmaceutical Review)

FDA-approved drug holds promise for first effective treatment to prevent trauma-induced heterotopic ossification formation...

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Recommended

Sirolimus

FDA awards 11 grants for rare disease treatment developments

Combining pacritinib with sirolimus-based GvHD prophylaxis may improve efficacy

Oral sirolimus alters the course of DIPNECH syndrome

Rapamycin treatment prevents crippling heterotopic ossification