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sartan

HPLC-MS/MS for NDMA impurity determination in sartans

28 September 2022 | By Hannah Balfour (European Pharmaceutical Review)

EPR summarises the development of a HPLC method for the detection, separation and quantification of N-nitrosodimethylamine (NDMA) in both olmesartan API and finished formulations.

man holding a clipboard in a suit overlaid on a close up of blue pills in a tube - idea of drug evaluation/approvals

news

CHMP recommends five medicines for approval in latest meeting

16 November 2020 | By Hannah Balfour (European Pharmaceutical Review)

The European Medicines Agency committee reports its November findings, including five drugs recommended for marketing authorisation.

news

EMA issues guidance on medicine impurities, in light of nitrosamine detection

24 June 2020 | By Victoria Rees (European Pharmaceutical Review)

After nitrosamines were detected in sartan medicines, the EMA has released new recommendations about handling and reporting impurities in drugs.

news

EMA to provide guidance on avoiding nitrosamines in medicines

17 September 2019 | By Victoria Rees (European Pharmaceutical Review)

The EMA has announced it is drafting guidance on how to avoid the presence of nitrosamines, a probable carcinogenic ingredient, in drugs.

news

Blood pressure and heart medication recalled by MHRA in UK

4 January 2019 | By Iqra Farooq (European Pharmaceutical Review)

The MHRA have announced another sartan-containing drug product over fears that it is contaminated with the carcinogen N‑nitrosodiethylamine...

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Recommended

sartan

HPLC-MS/MS for NDMA impurity determination in sartans

CHMP recommends five medicines for approval in latest meeting

EMA issues guidance on medicine impurities, in light of nitrosamine detection

EMA to provide guidance on avoiding nitrosamines in medicines

Blood pressure and heart medication recalled by MHRA in UK