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BRII-198

3D rendering of antibody taking part in immune defense.

US closes enrolment in two COVID-19 antibody studies due to futility

5 March 2021 | By Hannah Balfour (European Pharmaceutical Review)

The sub-studies evaluating VIR-7831 and BRII-196 with BRII-198 have stopped enrolment based on recommendations from the Data and Safety Monitoring Board.

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Trial to assess AstraZeneca’s long-acting COVID-19 antibody therapy

9 February 2021 | By Hannah Balfour (European Pharmaceutical Review)

The ACTIV-3 sub-study will evaluate the safety and efficacy of the AZD7442 synthetic antibody combination in at least 150 participants with mild-to-moderate COVID-19.

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Study finds some antibody therapies are not effective against new COVID-19 variants

28 January 2021 | By Hannah Balfour (European Pharmaceutical Review)

In vitro neutralisation assays show REGEN-COV and AZD7442 are effective against the new SARS-CoV-2 variants, while other antibody therapies, including Eli Lilly’s bamlanivimab, were not.

antibodies attacking an orange coronavirus particle

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Trial to evaluate monoclonal antibody therapy for mild-to-moderate COVID-19

6 January 2021 | By Hannah Balfour (European Pharmaceutical Review)

The study will determine if the combination of BRII-196 and BRII-198, two investigational antibodies for SARS-CoV-2, can prevent disease progression.

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Recommended

BRII-198

US closes enrolment in two COVID-19 antibody studies due to futility

Trial to assess AstraZeneca’s long-acting COVID-19 antibody therapy

Study finds some antibody therapies are not effective against new COVID-19 variants

Trial to evaluate monoclonal antibody therapy for mild-to-moderate COVID-19