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Pancreatic ductal adenocarcinoma (PDAC)

Could personalised mRNA vaccine be first for cancer?

12 May 2023 | By Catherine Eckford (European Pharmaceutical Review)

Half of pancreatic ductal adenocarcinoma (PDAC) patients given a personalised mRNA neoantigen vaccine experienced delayed recurrence 18 months post-vaccination.

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Onivyde^® improves survival in Phase III pancreatic cancer trial

23 January 2023 | By Catherine Eckford (European Pharmaceutical Review)

Onivyde® (irinotecan liposome injection) treatment regimen significantly improved survival in a Phase III trial compared to nab-paclitaxel plus gemcitabine.

news

Individualised mRNA vaccine shows promise in pancreatic cancer patients

8 June 2022 | By Sarah Wills (European Pharmaceutical Review)

Phase I study shows that mRNA-based individualised neoantigen specific immunotherapy (iNeST) vaccines can be used to stimulate T cells to recognise neoantigens in pancreatic cancer patients.

realistic image of a pancreas within the body cavity, with an orange section indication a cancerous pancreatic tumour

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Triple combination of therapies shows promise in pancreatic cancer trial

17 December 2020 | By Hannah Balfour (European Pharmaceutical Review)

The combination of motixafortide, KEYTRUDA® and chemotherapy met all trial endpoints, including increasing overall and progression free survival.

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Recommended

Pancreatic ductal adenocarcinoma (PDAC)

Could personalised mRNA vaccine be first for cancer?

Onivyde® improves survival in Phase III pancreatic cancer trial

Individualised mRNA vaccine shows promise in pancreatic cancer patients

Triple combination of therapies shows promise in pancreatic cancer trial

Onivyde^® improves survival in Phase III pancreatic cancer trial