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Nonalcoholic steatohepatitis (NASH)

FDA approval could shape liver disease treatment landscape

15 March 2024 | By Catherine Eckford (European Pharmaceutical Review)

A novel liver therapy authorised under US Food and Drug Administration (FDA) Accelerated Approval, is a potential game-changer in the NASH treatment space.

news

Boehringer Ingelheim agrees $2bn siRNA therapeutic collaboration

3 January 2024 | By Catherine Eckford (European Pharmaceutical Review)

The collaboration seeks to develop new siRNA treatments for the liver diseases nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH).

article

Developing novel therapies for NASH

24 March 2023 | By Catherine Eckford (European Pharmaceutical Review), Dr Hank Mansbach (89bio)

In this exclusive interview, Dr Hank Mansbach, Chief Medical Officer of 89bio discusses clinical development of FGF21 therapy to treat fatty liver disease.

close up of the hands of a group of business people piled together in the middle of a circle - idea of collaboration

article

Collaboration and integration to progress clinical research

6 August 2021 | By Hannah Balfour (European Pharmaceutical Review)

Here, Lucinda Cash-Gibson and Francesco Patalano discuss why the pharmaceutical industry is collaborating to develop protocols for patient-centric integrated platform trials and what the clinical research industry may look like in future.

news

ASC40 meaningfully reduces liver fat in Phase II NASH trial

9 March 2021 | By Hannah Balfour (European Pharmaceutical Review)

ASC40 reduced liver fat and significantly lowered an enzyme associated with liver inflammation in nonalcoholic steatohepatitis (NASH) patients.

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