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Melanoma & Skin Cancer

NICE says ‘yes’ to Opdivo (nivolumab) in melanoma

22 January 2016 | By Victoria White

NICE recommends that nivolumab is made available on the NHS as a treatment option for patients with advanced (unresectable or metastatic) melanoma...

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Trial of IMCgp100, durvalumab and tremelimumab in melanoma starts

20 January 2016 | By Victoria White

Immunocore has announced the start of the Phase Ib/II combination trial evaluating IMCgp100 with durvalumab and tremelimumab for the treatment of metastatic cutaneous melanoma...

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EC approves Imlygic as Europe’s first oncolytic immunotherapy

18 December 2015 | By Victoria White

The European Commission has approved the use of Amgen’s Imlygic (talimogen laherparepvec) for the treatment of adults with unresectable melanoma...

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EC approves Cotellic plus Zelboraf in advanced melanoma

25 November 2015 | By Victoria White

The approval is based on data that showed Cotellic plus Zelboraf helped people with previously untreated BRAF V600 mutation-positive advanced melanoma live for more than a year without their disease worsening...

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Merck announces findings from Keytruda combination studies

23 November 2015 | By Victoria White

The findings come from three studies investigating the use of Keytruda (pembrolizumab) in combination with three other immunotherapies – epacadostat, Imlygic (talimogene laherparepvec), and ipilimumab – in patients with advanced melanoma...

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FDA grants Breakthrough Therapy designation to avelumab for MCC

18 November 2015 | By Victoria White

Avelumab (MSB0010718C) is an investigational fully human anti-PD-L1 IgG1 monoclonal antibody...

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FDA approves Cotellic plus Zelboraf in advanced melanoma

11 November 2015 | By Victoria White

The approval is for the treatment of people with BRAF V600E or V600K mutation-positive unresectable or metastatic melanoma...

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FDA approves Yervoy as adjuvant treatment for stage III melanoma

29 October 2015 | By Victoria White

This approval is based on clinical data from a pivotal Phase 3 trial which demonstrated Yervoy significantly improved recurrence-free survival vs. placebo in this setting...

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FDA approves Imlygic for the treatment of melanoma lesions

28 October 2015 | By Victoria White

Imylgic is a genetically modified herpes simplex virus type 1 designed to replicate within tumours and produce an immunostimulatory protein called GM-CSF...

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CHMP adopts positive opinion for melanoma treatment Imlygic

23 October 2015 | By Victoria White

If approved by the European Commission, Imlygic would be the first in a class of novel agents known as oncolytic immunotherapies...

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Incyte and Merck to investigate epacadostat and Keytruda in melanoma

13 October 2015 | By Victoria White

Preclinical evidence suggests that the combination of these two agents may lead to an enhanced anti-tumour immune response...

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Another NICE recommendation for melanoma drug Keytruda

9 October 2015 | By Victoria White

This new recommendation for Keytruda is for treating advanced melanoma that has not been previously treated with ipilimumab...

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NICE says ‘yes’ to pembrolizumab for advanced melanoma

7 October 2015 | By

Pembrolizumab was the first drug to be approved through the Medicines and Healthcare Products Regulatory Agency’s Early Access to Medicine Scheme (EAMS)...

news

Cotellic Zelboraf combo demonstrates significant overall survival results

6 October 2015 | By Victoria White

Results from a Phase III study show that Cotellic plus Zelboraf helped people with advanced melanoma live significantly longer compared to Zelboraf alone...

news

FDA approves Opdivo + Yervoy in melanoma

1 October 2015 | By Victoria White

The announcement marks the first and only FDA approval of a Regimen of two immuno-oncology agents in cancer...

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Melanoma & Skin Cancer