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Close up of blue and white tablets spilling out of a medicine bottle onto a table with blurred background - idea of solid form narrow therapeutic index drugs
Close up of blue and white tablets spilling out of a medicine bottle onto a table with blurred background - idea of solid form narrow therapeutic index drugs
article

Physicochemical failure modes for first-line therapy Narrow Therapeutic Index (NTI) drugs: a call for attention NTI risk classification and New Prior Knowledge

2 July 2021 | By , , ,

In this article, Dr Harsh Shah and colleagues summarise their research into the importance of characterising physicochemical characteristics that can result in stress-induced solid-state changes in Narrow Therapeutic Index (NTI) drugs.