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diffuse large B-cell lymphoma (DLBCL)

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EMA human medicines committee (CHMP) highlights, September 2022

21 September 2022 | By Hannah Balfour (European Pharmaceutical Review)

In its latest meeting, the Committee for Medicinal Products for Human Use (CHMP) recommended 12 medicines for approval, including those for rare diseases, osteoporosis and cancer.

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CHMP meeting highlights, January 2022

28 January 2022 | By Hannah Balfour (European Pharmaceutical Review)

The EMA’s Human Medicines Committee (CHMP) recommended approval of Paxlovid for COVID-19 and a new gene therapy for large B-cell lymphomas.

Photomicrograph of diffuse B-cell lymphoma

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Minjuvi^® receives EC approval to treat large B-cell lymphoma

27 August 2021 | By Anna Begley (European Pharmaceutical Review)

European Commission (EC) approves Minjuvi with lenalidomide for the treatment of large B-cell lymphoma in adults.

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Pfizer to acquire Trillium immuno-oncology therapeutics

24 August 2021 | By Anna Begley (European Pharmaceutical Review)

Pfizer will acquire Trillium Therapeutics, an immuno-oncology company, potentially enhancing growth of cancer treatments from 2026.

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Polivy^® with R-CHP significantly improves lymphoma outcomes

9 August 2021 | By Anna Begley (European Pharmaceutical Review)

Polivy

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EMA human medicines committee meeting highlights, June 2021

25 June 2021 | By Hannah Balfour (European Pharmaceutical Review)

Drugs recommended for approval by the European Medicines Agency’s human medicines committee included a gene therapy and two generics, among five others.

Red CAR T cells attacking a central larger white 'cancer' cell on a dark turquoise background - idea of CAR T-cell therapy

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CAR T therapy provides long-lasting remissions in non-hodgkin lymphoma

19 February 2021 | By Hannah Balfour (European Pharmaceutical Review)

Study shows most non-Hodgkin's lymphoma patients who achieve a remission lasting one year remain in remission for five years after receiving Novartis’ Kymriah™.

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FDA approves third gene therapy for large B-cell lymphoma

8 February 2021 | By Hannah Balfour (European Pharmaceutical Review)

Breyanzi (lisocabtagene maraleucel) was approved on the 54 percent complete remission rate achieved in diffuse large B-cell lymphoma trials.

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Gilead set to acquire Forty Seven for $4.9bn later in 2020

5 March 2020 | By Hannah Balfour (European Pharmaceutical Review)

Gilead's acquisition of Forty Seven was unanimously approved by both companies' Boards of Directors, for $95.50 per share.

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NICE does not recommend polatuzumab vedotin to treat lymphoma

27 February 2020 | By Victoria Rees (European Pharmaceutical Review)

NICE has formed a negative opinion for Polivy (polatuzumab vedotin) in combination with rituximab and bendamustine to treat diffuse large B-cell lymphoma.

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Scottish Medicines Consortium approves Kymriah^® CAR-T therapy

10 September 2019 | By Victoria Rees (European Pharmaceutical Review)

The Kymriah (tisagenlecleucel) treatment has received a positive appraisal from the Scottish Medicines Consortium, after EMA approval last year.

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Global 2-year trial reports on CAR-T therapy to treat DLBCL

3 December 2018 | By European Pharmaceutical Review

A study has reported results of a clinical trial using CAR-T therapy where over half of the cancer patients were alive two years after the start...

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diffuse large B-cell lymphoma (DLBCL)