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Computational method could reduce the risk of drug formulations
A team of researchers have developed a computational method using an algorithm to develop formulations for drugs so they function properly...
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Formulation
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Growing role of personalised and precision medicine in cancer treatments
The role of personalised and precision medicine may be ideal for the treatment of cancer, but questions about consequences and society issues still remain...
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Making liposomal formulations for the delivery of RNA vaccines
A Dolomite Microfluidics’ set-up for high throughput single cell encapsulation is helping researchers at the Department of Medicine at Imperial College, London, to develop novel liposomal formulations for RNA vaccines targeting diseases such as HIV, influenza, rabies and chlamydia...
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Freeze-dried TB vaccine candidate enters Phase 1 human clinical trial
A vaccine that does not require a cold chain could be much more easily distributed to communities in need…
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Lithium treatment and GKS3 suppression could lead to kidney failure
Researchers have warned that certain psychiatric medications and treatments for bipolar disease could lead to the development of kidney failure...
whitepaper
Whitepaper: Solubility: Importance, measurements and applications
The solubility of a compound in organic solvents or water is equally important for screen design and later for process development.
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Learning the unwritten rules and dynamics of power
As part of EPR’s Women in Pharma series, Nawal Ouzren, CEO of Sensorion, talks to Science Editor Dr Zara Kassam about the diversity in drug development, creating a new growth mindset and elevating conversations beyond obvious beliefs...
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Computer programme that could bypass patents to produce synthetic drugs
Software that can bypass current intellectual property and design medication with the same function as top drugs could help pharma companies...
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The obstacle to developing an optimum placebo formulation for pharmaceutical freeze drying
Scale-up of pharmaceutical freeze-drying processes is cost and time consuming due to Quality by Design (QbD) requirements and novel compound costs or availability. The application of placebo formulations offers a promising way to improve drug development activities and save resources. Furthermore, placebos are used as a reference in clinical trials.…
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Almac Group extends personalised cancer vaccine production facilities
The Almac Group, a CDMO serving the pharmaceutical and biotech sectors globally, is expanding its Edinburgh Technopole facility to allow scale-up of its personalised cancer vaccine activities...
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The future of precision medicine
As part of EPR’s Women in Pharma series, Ruth March, VP and Head of Precision Medicine and Genomics at AstraZeneca, talks to Science Editor Dr Zara Kassam about decreasing the clinical risk associated with solid tumour biopsy, balancing a scientific career with family life and taking advantage of company initiatives…
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Inhaled dry powder formulation of treprostinil works well in PAH patients
A formulation of treprostinil as an inhaled dry powder has proven to be safe and effective, as reported in the safety analysis of a Phase III trial...
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Developing the production of the radioisotope Tc-99m within the US
A team of university researchers have collaborated together to develop a method to produce the radioisotope Tc-99m in the US to prevent having to import it...
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Diversifying drug development with a metal catalyst
Researchers have outlined a method of formulating drug-like aliphatic and aromatic carbon-hydrogen scaffolds into drugs using a metal catalyst...
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Deloitte finds Pharma returns on R&D reach new low
Deloitte has found a sharp decline in the returns on investment from top pharmaceutical companies, with returns at almost half of what they were in 2010...
