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Analytical techniques

 

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Applying simple PAT tools to crystallisation in process chemistry

23 October 2017 | By

Crystallisation is a common step in the synthesis of organic compounds used to isolate and purify the desired product. As the importance of crystallisation has increased and chemists improve the processes involved, process analytical technology (PAT) tools can be used to design, analyse, and control them. This article considers the…

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Determination of glucosamine in food supplements by HILIC-ESI-MS

20 October 2017 | By , , ,

Glucosamine is sold as a food supplement worldwide, but its production is poorly regulated. A direct and reliable method for the quality control of glucosamine in commercial products is of great importance. This article describes a simple, fast and validated ultra-performance liquid chromatography-quadrupole time of flight (UPLC-QToF) for the determination…

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Microbiology In-Depth Focus 2017

19 October 2017 | By

The European Pharmacopoeia chapter on methods for microbiological quality control was recently revised to include a number of significant changes. In this In-Depth Focus Michael Miller provides the first part of this two-part review and Kevin Williams discusses a paradigm change in biologics microbiological contaminant control.

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Guide to Outsourcing

18 October 2017 | By

Welcome to European Pharmaceutical Review’s Guide to Outsourcing, the fourth in our series of ‘Guide to…’ supplements. In this edition, five leading companies that provide outsourcing services explain how their portfolio meets current industry needs.

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Thermo Scientific TruScan RM Analyzer with TruTools

4 October 2017 | By

THERMO FISHER SCIENTIFIC explains how it provides industry-leading handheld Raman spectroscopy for qualitative and quantitative analysis of ingredients and excipients. Its TruScan RM Analyzer with TruTools embedded chemometrics package provides users with the flexibility to build customised qualitative and quantitative methods for complex material analysis problems...