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The purpose of process development in pharma is to select and optimise a synthetic route to produce the active pharmaceutical ingredient (API) by the safest, cheapest, fastest, and cleanest (by green chemistry where possible) route, following both Good Laboratory Practice (GLP) and Quality by Design (QbD) principles.
A sprayable gel containing calcium carbonate nanoparticles with antibodies targeted to block CD47, could be the future of drug delivery for cancer...
HPLC is a rapid, accurate and sensitive method for determination of pharmaceutical drugs, degradations and impurity profiling. It is a preferred method for analytical characterisation during drug development.
The screening of leukaemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for AML...
Oxybutynin could help breast cancer survivors who are affected by increased hot flushes through cancer treatment, improving their quality of life...
The US FDA has announced that it will confirm the capability of five more countries to carry out good manufacturing practice (GMP)...
Research into detecting tau proteins in the brains of Alzheimer's patients has shown that a specific tracer could detect and measure the protein levels...
A phase III clinical trial showed that neoadjuvant chemotherapy and trastuzumab reduced the risk of recurrence of HER2-positive early-stage breast cancer...
A team of Iranian researchers have determined that trastuzumab taken with a heart drug leads to less heart damage in breast cancer patients...
Through a clinical trial, Cleveland researchers have identified how rivaroxaban reduces blood clots in cancer patients and also decreases related deaths...
Researchers have developed a method of using less contrast medium to still obtain high quality images in magnetic resonance imaging (MRI)...
A tiny microneedle patch could be the future of delivering therapeutic cell related drugs to the heart of patients after a heart attack...
Metrohm USA is proud to continue its productive collaboration with USP on a global initiative to modernise monographs that have traditionally featured wet chemistry methods...
A nanoscale blood test could be used to gain more information from the blood of patients in order to help the identification of cancer in its early stages...
A gene therapy called AAV2-GAD has been associated with improved motor function, leading to researchers looking at its use in an upcoming Phase III trial...
