Prescribed opioids raise risk of pneumonia
A study has found that opioids, including morphine, codeine and fentanyl increase the likelihood of patients being affected by pneumonia...
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A study has found that opioids, including morphine, codeine and fentanyl increase the likelihood of patients being affected by pneumonia...
A complete workflow to quantify intact therapeutic proteins in plasma matrix has been developed, covering three critical components in preclinical sample analysis: target protein enrichment/purification, LC/MS data acquisition and quantitative data analysis.
Ustekinumab has been submitted to be the first interleukin (IL)-12/23 inhibitor licensed for the treatment of ulcerative colitis...
The results of a long-term study on the use of ADHD medication has advised that they are unlikely to result in heart damage, or cardiac difficulties...
Deloitte has found a sharp decline in the returns on investment from top pharmaceutical companies, with returns at almost half of what they were in 2010...
A clinical trial to analyse breath for volatile organic compounds to detect different types of cancer has been launched by Cancer Research UK...
A study has found that when compared with other drugs, canagliflozin may not be associated with fractures in patients with diabetes...
Minority underrepresentation in clinical trials for drugs to treat MS has led to doctors being unable to make informed decisions when prescribing...
Standard excipients can be sourced from various suppliers, but what if you need to customise an excipient to suit your needs?
The FDA’s Quality by Design (QbD) initiative brought a paradigm shift to pharmaceutical manufacturing and leading manufacturers have realised improved processes after adopting QbD. Raman spectroscopy is an established Process Analytical Technology (PAT), enabling QbD and continuous approaches to pharmaceutical manufacturing.1
The Monocyte Activation Test (MAT) is used to detect or quantify pyrogenic substances that activate human monocytes.
Sophisticated hardware and software offer speed and precision. Pharmaceutical development often involves samples in solution or on transparent substrates. For these applications, confocal Raman imaging using an inverted beam path is an especially versatile and powerful investigative method.
The evolution of antibody-drug conjugates (ADCs) is a spectacular example of how global research can sculpt a new technology. Years of molecular and cell biology, conjugation chemistry and immunology progress has enabled a cytotoxic agent paired with a tumour-specifi c antibody to become mainstream cancer therapy.1 Today, advances continue, explains…
Used to detect a broad range of pyrogens in parenteral products including pharmaceuticals, biopharmaceuticals and medical devices, the Monocyte Activation Test (MAT) gives an in vitro alternative to conventional animal testing in accordance with regulatory guidelines.