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Diversifying drug development with a metal catalyst
Researchers have outlined a method of formulating drug-like aliphatic and aromatic carbon-hydrogen scaffolds into drugs using a metal catalyst...
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Analytical techniques
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Protein map using MS-based analysis shared in open database
Study using mass spectrometry-based analysis provides a greater understanding of the cell and a comprehensive map of cell proteins...
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Polish researchers develop method to recycle pharma packaging
The development of a process to recycle pharmaceutical waste products has led to the recovery of aluminum and polyvinyl chloride (PVC) from blister packs...
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Treating malaria using artemisinin-based combination therapy (ACT)
The artemisinin-based combination therapy (ACT), pyronaridine-artesunate, has been shown to be as effective in treating malaria as other drugs...
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The greener alternative for drug production
Researchers have developed a method using environmentally-friendly water and stable bonding between carbon and manganese instead of highly reactive metals...
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Clinically relevant dissolution specifications: selection and assessment
Setting specifications for new oral products can be challenging. Too lenient, and there is a risk of passing batches of inadequate quality; too stringent, and there is a risk of rejecting acceptable batches.
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Hormone therapy could be key in treating knee osteoarthritis
A study has found that the prevalence of knee osteoarthritis was significantly lower in participants using hormone therapy than those not taking hormones...
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Pharmaceutical corridor between Hong Kong and Brussels opens
The pharma corridor between Hong Kong and Brussels Airport assures handling quality for temperature-sensitive pharmaceuticals.
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Prescribed opioids raise risk of pneumonia
A study has found that opioids, including morphine, codeine and fentanyl increase the likelihood of patients being affected by pneumonia...
whitepaper
Application Note: Quantitation of intact therapeutic protein in plasma matrix by LC/MS
A complete workflow to quantify intact therapeutic proteins in plasma matrix has been developed, covering three critical components in preclinical sample analysis: target protein enrichment/purification, LC/MS data acquisition and quantitative data analysis.
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Ustekinumab could be approved to treat ulcerative colitis
Ustekinumab has been submitted to be the first interleukin (IL)-12/23 inhibitor licensed for the treatment of ulcerative colitis...
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ADHD drugs unlikely to cause cardiac damage in children
The results of a long-term study on the use of ADHD medication has advised that they are unlikely to result in heart damage, or cardiac difficulties...
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Deloitte finds Pharma returns on R&D reach new low
Deloitte has found a sharp decline in the returns on investment from top pharmaceutical companies, with returns at almost half of what they were in 2010...
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Clinical trial to develop breath test for cancer launched
A clinical trial to analyse breath for volatile organic compounds to detect different types of cancer has been launched by Cancer Research UK...
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Canagliflozin may not be associated with fracture risk in diabetes patients
A study has found that when compared with other drugs, canagliflozin may not be associated with fractures in patients with diabetes...
