news
Six new licensing deals for drug and gene therapy development firm
Oxford Genetics has won six new licensing deals for its scalable drug and gene therapy manufacturing in the synthetic biology sector...
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Analytical techniques
article
Open data policies in proteomics are starting to revolutionise the field
High-throughput mass spectrometry (MS)-based proteomics approaches have developed enormously in recent years and are continuing to do so. The current trend sees proteomics being used by academia and industry to tackle intricate biological questions, often in conjunction with other high-throughput “omics” disciplines such as genomics, transcriptomics and metabolomics. Within the…
news
New microscope offers options for drug discovery, safety
Researchers have developed a microscope that may provide insight into how safely and effectively a drug will perform in the body...
news
Darolutamide NDA to treat non-metastatic castration-resistant prostate cancer
A New Drug Application has been made to the US Food and Drug Administration for the drug darolutamide to treat non-metastatic prostate cancer...
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Near-infrared spectroscopy has grown up and moved from the lab to its own place
For decades, near-infrared (NIR) spectroscopy has been an invaluable tool within the laboratory and, interestingly, despite all the excellent instrumentation and technologies introduced for process control, NIR is still the most popular and mature technique available. This article will discuss the impact of NIR in pharmaceuticals from the perspective of…
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Online drying process control of pharmaceutical intermediates using near-infrared spectroscopy in a bypass system
Strong regimentation and economic interests demand the development and implementation of new techniques for process control and analysis in the pharmaceutical industry. The extensive analysis of all deployed materials, intermediates and products leads to a higher degree of process stability and can contribute to a faster compensation for deviations, especially…
news
Expansion of the global antibiotics market size
The global antibiotics market is set to increase at a CAGR of 4 percent to $62.06 billion, due to the rising prevalence of infectious diseases...
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Mass Spectrometry In-Depth Focus 2019
In this issue: identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS, and open data policies in proteomics.
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Identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS
Matrix-assisted laser desorption/ionisation (MALDI) time-of-flight (TOF) mass spectrometry (MS) has proven to be an excellent technique for identification of illegally distributed peptides and proteins for human use. The identification of proteins is mainly based on peptide mass fingerprinting (PMF) – ie, the bottom-up approach – while the small proteins and…
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NIR In-Depth Focus 2019
This near-infrared spectroscopy In-Depth Focus looks at online drying process control of pharmaceutical intermediates and how NIR has moved on from the lab.
news
Danaher acquires GE biopharma for $21.4 billion
General Electric is selling its biopharma business for $21.4 billion, with shares in the company jumping 16 percent upon the news...
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Guide to Analytical Testing 2019
In this edition of our 'Guide to' series we look at analytical testing instruments from SUEZ.
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European Pharmaceutical Review Issue 1 2019
In this issue we look at the challenges of shipping temperature-controlled products, the potential use of blockchain for pharma, and using MALDI-TOF for identification of peptides in suspected illegal medicinal products. The edition also includes articles on aseptic containment, legal advice on licensing negotiations and an In-Depth Focus article from…
whitepaper
Whitepaper: Analytical criteria in bacterial endotoxin testing using LAL and rFC
This article covers the analytical criteria that apply to Bacterial Endotoxin Testing (BET) using Limulus Amebocyte Lysate (LAL) or recombinant Horseshoe crab Factor C (rFC) for the bioactivity determination of endotoxin in aqueous solutions, such as pharmaceuticals and medical device extracts. It explains the importance of these criteria for accurate…
news
‘Smart drug’ shows promise for metastatic triple-negative breast cancer
A study has shown that a 'smart drug' that delivers a toxic payload directly to tumour cells could be a possible treatment for breast cancer...
