news
US and China should collaborate more to bring AI to healthcare
New article says that to take full advantage of deep-learning solutions in healthcare, the US and China should collaborate, not compete.
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Analytical techniques
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Tecan Synergence™ offers comprehensive approach to OEM system development
Tecan Partnering has consolidated its extensive OEM system development services for life sciences and IVD instruments to create Tecan Synergence™.
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Case study: Merck Leverages Data and Analytics to Support New Continuous Drug Manufacturing Processes
Over the past couple of years, the European Medicines Agency and US Food and Drug Administration have given approvals to a handful of pharmaceutical companies to manufacture drug products using continuous manufacturing processes.
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Scientific poster: Chromatography essentials for performing perfect separations
This free poster compiles all basic chromatography principles needed to develop and run flash and prep HPLC methods.
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Application note: Rapid Analysis of Genotoxic Nitrosamines by HPLC-MS/MS
Genotoxic impurities (GTI’s) are intermediate, reactive products or degradants formed during drug synthesis, formulation or storage.
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Video: Automation for E&L analysis
Get a quick view of sample preparation and automation gear for E&L analysis.
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New predictive software could aid clinical trials
MIT researchers have developed an algorithm which uses a new technique to predict missing data from clinical trial information.
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On-demand webinar: Increasing Efficiency in the Pharma Analytical Workflow through Standards and Reference Materials
This presentation will provide method development guidance for the extraction and quantification of analytes using headspace SPME.
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Article: Tips & tricks: sensitivity gains in LC-MS
The prerequisite of any highly sensitive analysis via HPLC-MS (high performance liquid chromatography coupled to mass spectrometry) is the use of ultrapure solvents and reagents and careful handling of all associated materials, consumables, and systems.
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Video: ASMS 2019: timsTOF fleX – MALDI Guided SpatialOMx
Combining the world's fastest proteomics instrument with over 25 years of MALDI experience.
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Video: ASMS 2019: diaPASEF
The timsTOF Pro with diaPASEF enables deeper proteome coverage in a single 4D shotgun proteomics experiment, with highly reproducible qualitative and quantitative results - making it a near-ideal mass analyzer for proteomics.
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Assessing host cell protein contamination in biotechnological products
Purification of a drug from host cell protein contaminants can be challenging, with low-level contamination often remaining after purification. Vanda Dolabela de Magalhães shares discussions on the subject from six Brazilian companies working in the biotech field.
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Analytical methods used in obtaining higher order structure information from protein therapeutics
The efficacy, safety and pharmacokinetic properties of a protein therapeutic substantially depend on the molecule having the right structure. This article reviews current methods used for obtaining higher order structure information of biotherapeutics.
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On-demand webinar: 6 impacts of your membrane filtration funnel choice on your workflow
This seminar describes different membrane characteristics and provides guidance in selecting the right filtration devices for sample preparation following in vitro dissolution.
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Expert view: Raman spectroscopy
Many researchers are keen to find analytical solutions that generate the chemical fingerprint of a sample at the molecular and cellular level. Overcoming these problems is made possible by label-free techniques such as Raman, SPRi or particle size analysis. This brief overview will identify the benefits of Raman spectroscopy.
