article29 June 2021 | By Christopher H Taron (New England Biolabs [NEB]), Saulius Vainauskas (New England Biolabs [NEB]), Xiaofeng Shi (New England Biolabs [NEB])
Glycosylation of therapeutic proteins is important to biologic drug development and is a critical quality attribute that is monitored during manufacturing. Analysis of O-glycans is technically challenging compared to that of N-glycans. In this review, Xiaofeng Shi, Saulius Vainauskas and Christopher H Taron summarise current O-glycan analytical approaches, describe the…